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Exemestane's 17-hydroxylated metabolite exerts biological effects as an androgen.
Ariazi EA, Leitão A, Oprea TI, Chen B, Louis T, Bertucci AM, Sharma CG, Gill SD, Kim HR, Shupp HA, Pyle JR, Madrack A, Donato AL, Cheng D, Paige JR, Jordan VC. Ariazi EA, et al. Mol Cancer Ther. 2007 Nov;6(11):2817-27. doi: 10.1158/1535-7163.MCT-07-0312. Epub 2007 Nov 7. Mol Cancer Ther. 2007. PMID: 17989318
Emerging principles for the development of resistance to antihormonal therapy: implications for the clinical utility of fulvestrant.
Ariazi EA, Lewis-Wambi JS, Gill SD, Pyle JR, Ariazi JL, Kim HR, Sharma CG, Cordera F, Shupp HA, Li T, Jordan VC. Ariazi EA, et al. Among authors: ariazi jl. J Steroid Biochem Mol Biol. 2006 Dec;102(1-5):128-38. doi: 10.1016/j.jsbmb.2006.09.003. Epub 2006 Nov 7. J Steroid Biochem Mol Biol. 2006. PMID: 17085047 Free PMC article.
29 results