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Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists.
Franchini S, Manasieva LI, Sorbi C, Battisti UM, Fossa P, Cichero E, Denora N, Iacobazzi RM, Cilia A, Pirona L, Ronsisvalle S, Aricò G, Brasili L. Franchini S, et al. Among authors: arico g. Eur J Med Chem. 2017 Jan 5;125:435-452. doi: 10.1016/j.ejmech.2016.09.050. Epub 2016 Sep 17. Eur J Med Chem. 2017. PMID: 27689727 Free article.
Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives.
Franchini S, Battisti UM, Prandi A, Tait A, Borsari C, Cichero E, Fossa P, Cilia A, Prezzavento O, Ronsisvalle S, Aricò G, Parenti C, Brasili L. Franchini S, et al. Among authors: arico g. Eur J Med Chem. 2016 Apr 13;112:1-19. doi: 10.1016/j.ejmech.2016.01.059. Epub 2016 Feb 1. Eur J Med Chem. 2016. PMID: 26874044 Free article.
Structure-Activity Relationships within a Series of σ1 and σ2 Receptor Ligands: Identification of a σ2 Receptor Agonist (BS148) with Selective Toxicity against Metastatic Melanoma.
Franchini S, Sorbi C, Battisti UM, Tait A, Bencheva LI, Cichero E, Fossa P, Cilia A, Prezzavento O, Ronsisvalle S, Aricò G, Benassi L, Vaschieri C, Azzoni P, Magnoni C, Brasili L. Franchini S, et al. Among authors: arico g. ChemMedChem. 2017 Nov 22;12(22):1893-1905. doi: 10.1002/cmdc.201700427. Epub 2017 Oct 30. ChemMedChem. 2017. PMID: 28940806 Free article.
Evaluation of N-substitution in 6,7-benzomorphan compounds.
Pasquinucci L, Prezzavento O, Marrazzo A, Amata E, Ronsisvalle S, Georgoussi Z, Fourla DD, Scoto GM, Parenti C, Aricò G, Ronsisvalle G. Pasquinucci L, et al. Among authors: arico g. Bioorg Med Chem. 2010 Jul 15;18(14):4975-82. doi: 10.1016/j.bmc.2010.06.005. Epub 2010 Jun 9. Bioorg Med Chem. 2010. PMID: 20599386
Synthesis and resolution of cis-(+/-)-methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperidin-1-yl)methyl]-1-(4-methylphenyl)cyclopropanecarboxylate [(+/-)-PPCC)]: new sigma receptor ligands with neuroprotective effect.
Prezzavento O, Campisi A, Parenti C, Ronsisvalle S, Aricò G, Arena E, Pistolozzi M, Scoto GM, Bertucci C, Vanella A, Ronsisvalle G. Prezzavento O, et al. Among authors: arico g. J Med Chem. 2010 Aug 12;53(15):5881-5. doi: 10.1021/jm100116p. J Med Chem. 2010. PMID: 20684615
43 results