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Tetrazine-Ligated CRISPR sgRNAs for Efficient Genome Editing.
Chen Z, Devi G, Arif A, Zamore PD, Sontheimer EJ, Watts JK. Chen Z, et al. Among authors: arif a. ACS Chem Biol. 2022 May 20;17(5):1045-1050. doi: 10.1021/acschembio.2c00116. Epub 2022 Apr 21. ACS Chem Biol. 2022. PMID: 35446558 Free PMC article.
GTSF1 accelerates target RNA cleavage by PIWI-clade Argonaute proteins.
Arif A, Bailey S, Izumi N, Anzelon TA, Ozata DM, Andersson C, Gainetdinov I, MacRae IJ, Tomari Y, Zamore PD. Arif A, et al. Nature. 2022 Aug;608(7923):618-625. doi: 10.1038/s41586-022-05009-0. Epub 2022 Jun 30. Nature. 2022. PMID: 35772669 Free PMC article.
Relaxed targeting rules help PIWI proteins silence transposons.
Gainetdinov I, Vega-Badillo J, Cecchini K, Bagci A, Colpan C, De D, Bailey S, Arif A, Wu PH, MacRae IJ, Zamore PD. Gainetdinov I, et al. Among authors: arif a. Nature. 2023 Jul;619(7969):394-402. doi: 10.1038/s41586-023-06257-4. Epub 2023 Jun 21. Nature. 2023. PMID: 37344600 Free PMC article.
Improved cytosine base editors generated from TadA variants.
Lam DK, Feliciano PR, Arif A, Bohnuud T, Fernandez TP, Gehrke JM, Grayson P, Lee KD, Ortega MA, Sawyer C, Schwaegerle ND, Peraro L, Young L, Lee SJ, Ciaramella G, Gaudelli NM. Lam DK, et al. Among authors: arif a. Nat Biotechnol. 2023 May;41(5):686-697. doi: 10.1038/s41587-022-01611-9. Epub 2023 Jan 9. Nat Biotechnol. 2023. PMID: 36624149 Free PMC article.
690 results