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C75 is converted to C75-CoA in the hypothalamus, where it inhibits carnitine palmitoyltransferase 1 and decreases food intake and body weight.
Mera P, Bentebibel A, López-Viñas E, Cordente AG, Gurunathan C, Sebastián D, Vázquez I, Herrero L, Ariza X, Gómez-Puertas P, Asins G, Serra D, García J, Hegardt FG. Mera P, et al. Among authors: ariza x. Biochem Pharmacol. 2009 Mar 15;77(6):1084-95. doi: 10.1016/j.bcp.2008.11.020. Epub 2008 Nov 27. Biochem Pharmacol. 2009. PMID: 19094968
A straightforward synthesis of (-)-phaseolinic acid.
Amador M, Ariza X, Garcia J, Ortiz J. Amador M, et al. Among authors: ariza x. J Org Chem. 2004 Nov 12;69(23):8172-5. doi: 10.1021/jo048705x. J Org Chem. 2004. PMID: 15527317
Stereoselective synthesis of (-)-spicigerolide.
Georges Y, Ariza X, Garcia J. Georges Y, et al. Among authors: ariza x. J Org Chem. 2009 Mar 6;74(5):2008-12. doi: 10.1021/jo8025753. J Org Chem. 2009. PMID: 19196165
Total synthesis of (-)-isoavenaciolide.
Santos D, Ariza X, Garcia J, Lloyd-Williams P, Martínez-Laporta A, Sánchez C. Santos D, et al. Among authors: ariza x. J Org Chem. 2013 Feb 15;78(4):1519-24. doi: 10.1021/jo302598h. Epub 2013 Jan 31. J Org Chem. 2013. PMID: 23339655 Free article.
68 results