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Loss of 5α-reductase type 1 accelerates the development of hepatic steatosis but protects against hepatocellular carcinoma in male mice.
Dowman JK, Hopkins LJ, Reynolds GM, Armstrong MJ, Nasiri M, Nikolaou N, van Houten EL, Visser JA, Morgan SA, Lavery GG, Oprescu A, Hübscher SG, Newsome PN, Tomlinson JW. Dowman JK, et al. Among authors: armstrong mj. Endocrinology. 2013 Dec;154(12):4536-47. doi: 10.1210/en.2013-1592. Epub 2013 Sep 30. Endocrinology. 2013. PMID: 24080367 Free PMC article.
Development of hepatocellular carcinoma in a murine model of nonalcoholic steatohepatitis induced by use of a high-fat/fructose diet and sedentary lifestyle.
Dowman JK, Hopkins LJ, Reynolds GM, Nikolaou N, Armstrong MJ, Shaw JC, Houlihan DD, Lalor PF, Tomlinson JW, Hübscher SG, Newsome PN. Dowman JK, et al. Among authors: armstrong mj. Am J Pathol. 2014 May;184(5):1550-61. doi: 10.1016/j.ajpath.2014.01.034. Epub 2014 Mar 17. Am J Pathol. 2014. PMID: 24650559 Free PMC article.
Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study.
Armstrong MJ, Gaunt P, Aithal GP, Barton D, Hull D, Parker R, Hazlehurst JM, Guo K; LEAN trial team; Abouda G, Aldersley MA, Stocken D, Gough SC, Tomlinson JW, Brown RM, Hübscher SG, Newsome PN. Armstrong MJ, et al. Lancet. 2016 Feb 13;387(10019):679-690. doi: 10.1016/S0140-6736(15)00803-X. Epub 2015 Nov 20. Lancet. 2016. PMID: 26608256 Free article. Clinical Trial.
403 results