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Metabolomic and quality data for early and late passages of an antibody-producing industrial CHO cell line.
Data Brief. 2020 Nov 26;33:106591. doi: 10.1016/j.dib.2020.106591. eCollection 2020 Dec.
Data Brief. 2020.
PMID: 33318978
Free PMC article.
Effective temperature shift strategy development and scale confirmation for simultaneous optimization of protein productivity and quality in Chinese hamster ovary cells.
McHugh KP, Xu J, Aron KL, Borys MC, Li ZJ.
McHugh KP, et al. Among authors: aron kl.
Biotechnol Prog. 2020 May;36(3):e2959. doi: 10.1002/btpr.2959. Epub 2020 Jan 17.
Biotechnol Prog. 2020.
PMID: 31930722
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Metabolic understanding of disulfide reduction during monoclonal antibody production.
Cura AJ, Xu X, Egan S, Aron K, Jenkins L, Hageman T, Huang Y, Chollangi S, Borys M, Ghose S, Li ZJ.
Cura AJ, et al.
Appl Microbiol Biotechnol. 2020 Nov;104(22):9655-9669. doi: 10.1007/s00253-020-10916-1. Epub 2020 Sep 30.
Appl Microbiol Biotechnol. 2020.
PMID: 32997205
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A Metabolomics Approach to Increasing Chinese Hamster Ovary (CHO) Cell Productivity.
Yao G, Aron K, Borys M, Li Z, Pendse G, Lee K.
Yao G, et al.
Metabolites. 2021 Nov 30;11(12):823. doi: 10.3390/metabo11120823.
Metabolites. 2021.
PMID: 34940581
Free PMC article.
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Untargeted proteomics reveals upregulation of stress response pathways during CHO-based monoclonal antibody manufacturing process leading to disulfide bond reduction.
Park SY, Egan S, Cura AJ, Aron KL, Xu X, Zheng M, Borys M, Ghose S, Li Z, Lee K.
Park SY, et al. Among authors: aron kl.
MAbs. 2021 Jan-Dec;13(1):1963094. doi: 10.1080/19420862.2021.1963094.
MAbs. 2021.
PMID: 34424810
Free PMC article.
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