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Small molecule probes of protein aggregation.
Young LM, Ashcroft AE, Radford SE. Young LM, et al. Among authors: ashcroft ae. Curr Opin Chem Biol. 2017 Aug;39:90-99. doi: 10.1016/j.cbpa.2017.06.008. Epub 2017 Jun 22. Curr Opin Chem Biol. 2017. PMID: 28649012 Free article. Review.
An in vivo platform for identifying inhibitors of protein aggregation.
Saunders JC, Young LM, Mahood RA, Jackson MP, Revill CH, Foster RJ, Smith DA, Ashcroft AE, Brockwell DJ, Radford SE. Saunders JC, et al. Among authors: ashcroft ae. Nat Chem Biol. 2016 Feb;12(2):94-101. doi: 10.1038/nchembio.1988. Epub 2015 Dec 14. Nat Chem Biol. 2016. PMID: 26656088 Free PMC article.
Inducing protein aggregation by extensional flow.
Dobson J, Kumar A, Willis LF, Tuma R, Higazi DR, Turner R, Lowe DC, Ashcroft AE, Radford SE, Kapur N, Brockwell DJ. Dobson J, et al. Among authors: ashcroft ae. Proc Natl Acad Sci U S A. 2017 May 2;114(18):4673-4678. doi: 10.1073/pnas.1702724114. Epub 2017 Apr 17. Proc Natl Acad Sci U S A. 2017. PMID: 28416674 Free PMC article.
130 results