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A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers.
Natrajan R, Mackay A, Lambros MB, Weigelt B, Wilkerson PM, Manie E, Grigoriadis A, A'Hern R, van der Groep P, Kozarewa I, Popova T, Mariani O, Turaljic S, Furney SJ, Marais R, Rodruigues DN, Flora AC, Wai P, Pawar V, McDade S, Carroll J, Stoppa-Lyonnet D, Green AR, Ellis IO, Swanton C, van Diest P, Delattre O, Lord CJ, Foulkes WD, Vincent-Salomon A, Ashworth A, Stern MH, Reis-Filho JS. Natrajan R, et al. Among authors: ashworth a, a hern r. J Pathol. 2012 May;227(1):29-41. doi: 10.1002/path.4003. Epub 2012 Feb 23. J Pathol. 2012. PMID: 22362584 Free PMC article.
Functions of the BRCA1 and BRCA2 genes.
Bertwistle D, Ashworth A. Bertwistle D, et al. Among authors: ashworth a. Curr Opin Genet Dev. 1998 Feb;8(1):14-20. doi: 10.1016/s0959-437x(98)80056-7. Curr Opin Genet Dev. 1998. PMID: 9529600 Review.
New complexities for BRCA1 and BRCA2.
Kerr P, Ashworth A. Kerr P, et al. Among authors: ashworth a. Curr Biol. 2001 Aug 21;11(16):R668-76. doi: 10.1016/s0960-9822(01)00389-x. Curr Biol. 2001. PMID: 11525763 Free article. Review.
Phenotypic effects of heterozygosity for a BRCA2 mutation.
Warren M, Lord CJ, Masabanda J, Griffin D, Ashworth A. Warren M, et al. Among authors: ashworth a. Hum Mol Genet. 2003 Oct 15;12(20):2645-56. doi: 10.1093/hmg/ddg277. Epub 2003 Aug 19. Hum Mol Genet. 2003. PMID: 12928478
Hallmarks of 'BRCAness' in sporadic cancers.
Turner N, Tutt A, Ashworth A. Turner N, et al. Among authors: ashworth a. Nat Rev Cancer. 2004 Oct;4(10):814-9. doi: 10.1038/nrc1457. Nat Rev Cancer. 2004. PMID: 15510162 Review.
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, Santarosa M, Dillon KJ, Hickson I, Knights C, Martin NM, Jackson SP, Smith GC, Ashworth A. Farmer H, et al. Among authors: ashworth a. Nature. 2005 Apr 14;434(7035):917-21. doi: 10.1038/nature03445. Nature. 2005. PMID: 15829967 Free article.
BRCA1 and BRCA2 as ovarian cancer susceptibility genes.
Sowter HM, Ashworth A. Sowter HM, et al. Among authors: ashworth a. Carcinogenesis. 2005 Oct;26(10):1651-6. doi: 10.1093/carcin/bgi136. Epub 2005 May 25. Carcinogenesis. 2005. PMID: 15917310
Targeting the DNA repair defect of BRCA tumours.
Turner N, Tutt A, Ashworth A. Turner N, et al. Among authors: ashworth a. Curr Opin Pharmacol. 2005 Aug;5(4):388-93. doi: 10.1016/j.coph.2005.03.006. Curr Opin Pharmacol. 2005. PMID: 15955736 Review.
822 results