Au-Yeung BB - Search Results

1

Itk controls the spatiotemporal organization of T cell activation.

Singleton KL, Gosh M, Dandekar RD, Au-Yeung BB, Ksionda O, Tybulewicz VL, Altman A, Fowell DJ, Wülfing C. Singleton KL, et al. Sci Signal. 2011 Oct 4;4(193):ra66. doi: 10.1126/scisignal.2001821. Sci Signal. 2011. PMID: 21971040 Free PMC article.

2

Cutting edge: Itk-dependent signals required for CD4+ T cells to exert, but not gain, Th2 effector function.

Au-Yeung BB, Katzman SD, Fowell DJ. Au-Yeung BB, et al. J Immunol. 2006 Apr 1;176(7):3895-9. doi: 10.4049/jimmunol.176.7.3895. J Immunol. 2006. PMID: 16547221

3

A key role for Itk in both IFN gamma and IL-4 production by NKT cells.

Au-Yeung BB, Fowell DJ. Au-Yeung BB, et al. J Immunol. 2007 Jul 1;179(1):111-9. doi: 10.4049/jimmunol.179.1.111. J Immunol. 2007. PMID: 17579028

4

Cbl-b mitigates the responsiveness of naive CD8⁺ T cells that experience extensive tonic T cell receptor signaling.

Eggert J, Zinzow-Kramer WM, Hu Y, Kolawole EM, Tsai YL, Weiss A, Evavold BD, Salaita K, Scharer CD, Au-Yeung BB. Eggert J, et al. Among authors: au yeung bb. Sci Signal. 2024 Feb 6;17(822):eadh0439. doi: 10.1126/scisignal.adh0439. Epub 2024 Feb 6. Sci Signal. 2024. PMID: 38319998 Free PMC article.

5

Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases.

Mukherjee S, Zhu J, Zikherman J, Parameswaran R, Kadlecek TA, Wang Q, Au-Yeung B, Ploegh H, Kuriyan J, Das J, Weiss A. Mukherjee S, et al. Sci Signal. 2013 Jan 1;6(256):ra1. doi: 10.1126/scisignal.2003220. Sci Signal. 2013. PMID: 23281368 Free PMC article.

6

A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity.

Au-Yeung BB, Levin SE, Zhang C, Hsu LY, Cheng DA, Killeen N, Shokat KM, Weiss A. Au-Yeung BB, et al. Nat Immunol. 2010 Dec;11(12):1085-92. doi: 10.1038/ni.1955. Epub 2010 Oct 31. Nat Immunol. 2010. PMID: 21037577 Free PMC article.

7

Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation.

Phee H, Au-Yeung BB, Pryshchep O, O'Hagan KL, Fairbairn SG, Radu M, Kosoff R, Mollenauer M, Cheng D, Chernoff J, Weiss A. Phee H, et al. Elife. 2014 May 13;3:e02270. doi: 10.7554/eLife.02270. Elife. 2014. PMID: 24843022 Free PMC article.

8

IL-2 Modulates the TCR Signaling Threshold for CD8 but Not CD4 T Cell Proliferation on a Single-Cell Level.

Au-Yeung BB, Smith GA, Mueller JL, Heyn CS, Jaszczak RG, Weiss A, Zikherman J. Au-Yeung BB, et al. J Immunol. 2017 Mar 15;198(6):2445-2456. doi: 10.4049/jimmunol.1601453. Epub 2017 Feb 3. J Immunol. 2017. PMID: 28159902 Free PMC article.

9

ZAP-70: an essential kinase in T-cell signaling.

Wang H, Kadlecek TA, Au-Yeung BB, Goodfellow HE, Hsu LY, Freedman TS, Weiss A. Wang H, et al. Cold Spring Harb Perspect Biol. 2010 May;2(5):a002279. doi: 10.1101/cshperspect.a002279. Cold Spring Harb Perspect Biol. 2010. PMID: 20452964 Free PMC article. Review.

10

Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development.

Au-Yeung BB, Melichar HJ, Ross JO, Cheng DA, Zikherman J, Shokat KM, Robey EA, Weiss A. Au-Yeung BB, et al. Nat Immunol. 2014 Jul;15(7):687-94. doi: 10.1038/ni.2918. Epub 2014 Jun 8. Nat Immunol. 2014. PMID: 24908390 Free PMC article.

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