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Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance.
Zhou D, Zhang Y, Wu H, Barry E, Yin Y, Lawrence E, Dawson D, Willis JE, Markowitz SD, Camargo FD, Avruch J. Zhou D, et al. Among authors: avruch j. Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):E1312-20. doi: 10.1073/pnas.1110428108. Epub 2011 Oct 31. Proc Natl Acad Sci U S A. 2011. PMID: 22042863 Free PMC article.
Protein kinases of the Hippo pathway: regulation and substrates.
Avruch J, Zhou D, Fitamant J, Bardeesy N, Mou F, Barrufet LR. Avruch J, et al. Semin Cell Dev Biol. 2012 Sep;23(7):770-84. doi: 10.1016/j.semcdb.2012.07.002. Epub 2012 Aug 9. Semin Cell Dev Biol. 2012. PMID: 22898666 Free PMC article. Review.
Characterization of two Mst1-deficient mouse models.
Anguera MC, Liu M, Avruch J, Lee JT. Anguera MC, et al. Among authors: avruch j. Dev Dyn. 2008 Nov;237(11):3424-34. doi: 10.1002/dvdy.21764. Dev Dyn. 2008. PMID: 18942145 Free PMC article.
Rassf family of tumor suppressor polypeptides.
Avruch J, Xavier R, Bardeesy N, Zhang XF, Praskova M, Zhou D, Xia F. Avruch J, et al. J Biol Chem. 2009 Apr 24;284(17):11001-5. doi: 10.1074/jbc.R800073200. Epub 2008 Dec 17. J Biol Chem. 2009. PMID: 19091744 Free PMC article. Review.
204 results