Azam T - Search Results

1

A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signaling.

Li S, Jiang L, Beckmann K, Højen JF, Pessara U, Powers NE, de Graaf DM, Azam T, Lindenberger J, Eisenmesser EZ, Fischer S, Dinarello CA. Li S, et al. Among authors: azam t. J Biol Chem. 2021 Jan-Jun;296:100630. doi: 10.1016/j.jbc.2021.100630. Epub 2021 Apr 3. J Biol Chem. 2021. PMID: 33823154 Free PMC article.

2

Site-specific mutations in the mature form of human IL-18 with enhanced biological activity and decreased neutralization by IL-18 binding protein.

Kim SH, Azam T, Yoon DY, Reznikov LL, Novick D, Rubinstein M, Dinarello CA. Kim SH, et al. Among authors: azam t. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3304-9. doi: 10.1073/pnas.051634098. Proc Natl Acad Sci U S A. 2001. PMID: 11248074 Free PMC article.

3

Identification of amino acid residues critical for biological activity in human interleukin-18.

Kim SH, Azam T, Novick D, Yoon DY, Reznikov LL, Bufler P, Rubinstein M, Dinarello CA. Kim SH, et al. Among authors: azam t. J Biol Chem. 2002 Mar 29;277(13):10998-1003. doi: 10.1074/jbc.M108311200. Epub 2002 Jan 14. J Biol Chem. 2002. PMID: 11790772 Free article.

4

The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines.

Leoni F, Zaliani A, Bertolini G, Porro G, Pagani P, Pozzi P, Donà G, Fossati G, Sozzani S, Azam T, Bufler P, Fantuzzi G, Goncharov I, Kim SH, Pomerantz BJ, Reznikov LL, Siegmund B, Dinarello CA, Mascagni P. Leoni F, et al. Among authors: azam t. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2995-3000. doi: 10.1073/pnas.052702999. Epub 2002 Feb 26. Proc Natl Acad Sci U S A. 2002. PMID: 11867742 Free PMC article.

5

Rat interleukin-18 binding protein: cloning, expression, and characterization.

Im SH, Kim SH, Azam T, Venkatesh N, Dinarello CA, Fuchs S, Souroujon MC. Im SH, et al. Among authors: azam t. J Interferon Cytokine Res. 2002 Mar;22(3):321-8. doi: 10.1089/107999002753675749. J Interferon Cytokine Res. 2002. PMID: 12034039

6

A complex of the IL-1 homologue IL-1F7b and IL-18-binding protein reduces IL-18 activity.

Bufler P, Azam T, Gamboni-Robertson F, Reznikov LL, Kumar S, Dinarello CA, Kim SH. Bufler P, et al. Among authors: azam t. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13723-8. doi: 10.1073/pnas.212519099. Proc Natl Acad Sci U S A. 2002. PMID: 12381835 Free PMC article.

7

Generation and characterization of mice transgenic for human IL-18-binding protein isoform a.

Fantuzzi G, Banda NK, Guthridge C, Vondracek A, Kim SH, Siegmund B, Azam T, Sennello JA, Dinarello CA, Arend WP. Fantuzzi G, et al. Among authors: azam t. J Leukoc Biol. 2003 Nov;74(5):889-96. doi: 10.1189/jlb.0503230. Epub 2003 Aug 11. J Leukoc Biol. 2003. PMID: 12960225

8

Identification of a critical Ig-like domain in IL-18 receptor alpha and characterization of a functional IL-18 receptor complex.

Azam T, Novick D, Bufler P, Yoon DY, Rubinstein M, Dinarello CA, Kim SH. Azam T, et al. J Immunol. 2003 Dec 15;171(12):6574-80. doi: 10.4049/jimmunol.171.12.6574. J Immunol. 2003. PMID: 14662859

9

Interleukin-1 homologues IL-1F7b and IL-18 contain functional mRNA instability elements within the coding region responsive to lipopolysaccharide.

Bufler P, Gamboni-Robertson F, Azam T, Kim SH, Dinarello CA. Bufler P, et al. Among authors: azam t. Biochem J. 2004 Jul 15;381(Pt 2):503-10. doi: 10.1042/BJ20040217. Biochem J. 2004. PMID: 15046617 Free PMC article.

10

Differences in signaling pathways by IL-1beta and IL-18.

Lee JK, Kim SH, Lewis EC, Azam T, Reznikov LL, Dinarello CA. Lee JK, et al. Among authors: azam t. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8815-20. doi: 10.1073/pnas.0402800101. Epub 2004 May 25. Proc Natl Acad Sci U S A. 2004. PMID: 15161979 Free PMC article.

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