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Cardiomyocyte-specific PCSK9 deficiency compromises mitochondrial bioenergetics and heart function.
Laudette M, Lindbom M, Arif M, Cinato M, Ruiz M, Doran S, Miljanovic A, Rutberg M, Andersson L, Klevstig M, Henricsson M, Bergh PO, Bollano E, Aung N, Gustav Smith J, Pilon M, Hyötyläinen T, Orešič M, Perkins R, Mardinoglu A, Levin MC, Borén J. Laudette M, et al. Among authors: miljanovic a. Cardiovasc Res. 2023 Jul 4;119(7):1537-1552. doi: 10.1093/cvr/cvad041. Cardiovasc Res. 2023. PMID: 36880401 Free PMC article.
Cardiac Plin5 interacts with SERCA2 and promotes calcium handling and cardiomyocyte contractility.
Cinato M, Mardani I, Miljanovic A, Drevinge C, Laudette M, Bollano E, Henricsson M, Tolö J, Bauza Thorbrügge M, Levin M, Lindbom M, Arif M, Pacher P, Andersson L, Olofsson CS, Borén J, Levin MC. Cinato M, et al. Among authors: miljanovic a. Life Sci Alliance. 2023 Jan 30;6(4):e202201690. doi: 10.26508/lsa.202201690. Print 2023 Apr. Life Sci Alliance. 2023. PMID: 36717246 Free PMC article.
Glucosylceramide synthase deficiency in the heart compromises β1-adrenergic receptor trafficking.
Andersson L, Cinato M, Mardani I, Miljanovic A, Arif M, Koh A, Lindbom M, Laudette M, Bollano E, Omerovic E, Klevstig M, Henricsson M, Fogelstrand P, Swärd K, Ekstrand M, Levin M, Wikström J, Doran S, Hyötyläinen T, Sinisalu L, Orešič M, Tivesten Å, Adiels M, Bergo MO, Proia R, Mardinoglu A, Jeppsson A, Borén J, Levin MC. Andersson L, et al. Among authors: miljanovic a. Eur Heart J. 2021 Nov 14;42(43):4481-4492. doi: 10.1093/eurheartj/ehab412. Eur Heart J. 2021. PMID: 34297830 Free PMC article.
Plin2-deficiency reduces lipophagy and results in increased lipid accumulation in the heart.
Mardani I, Tomas Dalen K, Drevinge C, Miljanovic A, Ståhlman M, Klevstig M, Scharin Täng M, Fogelstrand P, Levin M, Ekstrand M, Nair S, Redfors B, Omerovic E, Andersson L, Kimmel AR, Borén J, Levin MC. Mardani I, et al. Among authors: miljanovic a. Sci Rep. 2019 May 6;9(1):6909. doi: 10.1038/s41598-019-43335-y. Sci Rep. 2019. PMID: 31061399 Free PMC article.
Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia.
Klevstig M, Arif M, Mannila M, Svedlund S, Mardani I, Ståhlman M, Andersson L, Lindbom M, Miljanovic A, Franco-Cereceda A, Eriksson P, Jeppsson A, Gan LM, Levin M, Mardinoglu A, Ehrenborg E, Borén J. Klevstig M, et al. Among authors: miljanovic a. J Mol Cell Cardiol. 2019 Dec;137:1-8. doi: 10.1016/j.yjmcc.2019.09.003. Epub 2019 Sep 15. J Mol Cell Cardiol. 2019. PMID: 31533023 Free article.