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1988 1
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2005 1
2007 1
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2010 4
2011 1
2012 3
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2019 1
2020 2
2022 5
2023 2
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29 results

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Page 1
Th17 Cell-Derived Amphiregulin Promotes Colitis-Associated Intestinal Fibrosis Through Activation of mTOR and MEK in Intestinal Myofibroblasts.
Zhao X, Yang W, Yu T, Yu Y, Cui X, Zhou Z, Yang H, Yu Y, Bilotta AJ, Yao S, Xu J, Zhou J, Yochum GS, Koltun WA, Portolese A, Zeng D, Xie J, Pinchuk IV, Zhang H, Cong Y. Zhao X, et al. Among authors: koltun wa. Gastroenterology. 2023 Jan;164(1):89-102. doi: 10.1053/j.gastro.2022.09.006. Epub 2022 Sep 13. Gastroenterology. 2023. PMID: 36113570 Free PMC article.
Pathophysiology of diverticular disease.
Schieffer KM, Kline BP, Yochum GS, Koltun WA. Schieffer KM, et al. Among authors: koltun wa. Expert Rev Gastroenterol Hepatol. 2018 Jul;12(7):683-692. doi: 10.1080/17474124.2018.1481746. Epub 2018 Jun 7. Expert Rev Gastroenterol Hepatol. 2018. PMID: 29846097 Review.
Gastrointestinal hypoalgesia in inflammatory bowel disease.
Coates MD, Soriano C, Dalessio S, Stuart A, Walter V, Koltun W, Bernasko N, Tinsley A, Clarke K, Williams ED. Coates MD, et al. Among authors: koltun w. Ann Gastroenterol. 2020 Jan-Feb;33(1):45-52. doi: 10.20524/aog.2019.0442. Epub 2019 Nov 29. Ann Gastroenterol. 2020. PMID: 31892797 Free PMC article.
We compared demographic and clinical features in 3 patient cohorts defined using data from simultaneous pain surveys and ileocolonoscopy: a) active IBD without pain (hypoalgesic IBD); b) active IBD with pain; and c) inactive IBD without pain. RESULTS: One hundred fifty-thr …
We compared demographic and clinical features in 3 patient cohorts defined using data from simultaneous pain surveys and ileocolonoscopy: a) …
Tumor Treating Fields (TTFields) Concomitant with Immune Checkpoint Inhibitors Are Therapeutically Effective in Non-Small Cell Lung Cancer (NSCLC) In Vivo Model.
Barsheshet Y, Voloshin T, Brant B, Cohen G, Koren L, Blatt R, Cahal S, Haj Khalil T, Zemer Tov E, Paz R, Klein-Goldberg A, Tempel-Brami C, Jacobovitch S, Volodin A, Kan T, Koltun B, David C, Haber A, Giladi M, Weinberg U, Palti Y. Barsheshet Y, et al. Among authors: koltun b. Int J Mol Sci. 2022 Nov 15;23(22):14073. doi: 10.3390/ijms232214073. Int J Mol Sci. 2022. PMID: 36430552 Free PMC article.
Crystal Structure Analysis of 4-Oxo, 4-hydroxy- and 4-alkyl-7-bromopyrazolo[5,1-c][1,2,4]triazines.
Ivanov SM, Koltun DS. Ivanov SM, et al. Among authors: koltun ds. J Chem Crystallogr. 2022 Dec 17:1-12. doi: 10.1007/s10870-022-00973-x. Online ahead of print. J Chem Crystallogr. 2022. PMID: 36567741 Free PMC article.
The crystal structures of 8-R(1)-7-bromo-3-tert-butyl-1-R(2)-pyrazolo[5,1-c][1,2,4]triazin-4(1H)-ones 1a-c, 2a,c (R(1) = CN, CO(2)Et, NO(2), R(2) = H, 1:1 and 3:1 solvates with DMSO; R(1) = CN, CO(2)Et, R(2) = CH(2)Boc), 8-R(1)-7-bromo-3-tert-butyl-1-R(2)-1,4-dihydropyrazolo[5,1- …
The crystal structures of 8-R(1)-7-bromo-3-tert-butyl-1-R(2)-pyrazolo[5,1-c][1,2,4]triazin-4(1H)-ones 1a-c, 2a,c (R(1) = CN, CO(2)Et, NO(2), …
Association of diet quality and hormonal status in exercising women with menstrual disturbances.
Łagowska K, Strock NCA, Koltun KJ, Williams NI, De Souza MJ. Łagowska K, et al. Among authors: koltun kj. Appl Physiol Nutr Metab. 2022 Nov 1;47(11):1085-1095. doi: 10.1139/apnm-2021-0789. Epub 2022 Sep 9. Appl Physiol Nutr Metab. 2022. PMID: 36084338

Oligo/Amen-HighFAI group had the highest androgen concentrations (P < 0.05) and lower DQI-I score compared to OV group and Oligo/Amen-LowFAI (P < 0.05). The Oligo/Amen-HighFAI group consumed less of vitamin A, B(2), B(6), B(12), magnesium, and potassium

Oligo/Amen-HighFAI group had the highest androgen concentrations (P < 0.05) and lower DQI-I score compared to OV group and Oligo/Amen-Low

Identification of disease-associated DNA methylation in B cells from Crohn's disease and ulcerative colitis patients.
Lin Z, Hegarty JP, Yu W, Cappel JA, Chen X, Faber PW, Wang Y, Poritz LS, Fan JB, Koltun WA. Lin Z, et al. Among authors: koltun wa. Dig Dis Sci. 2012 Dec;57(12):3145-53. doi: 10.1007/s10620-012-2288-z. Epub 2012 Jul 21. Dig Dis Sci. 2012. PMID: 22821069
B cell DNA methylation markers are particularly favorable for diagnosis due to the convenient access to peripheral blood. ...To verify that observed changes in DNA methylation were not due to virus transformation, we compared specific CpG DNA methylation levels of GADD45A
B cell DNA methylation markers are particularly favorable for diagnosis due to the convenient access to peripheral blood. ...To verif
Indices of Resting Metabolic Rate Accurately Reflect Energy Deficiency in Exercising Women.
Strock NCA, Koltun KJ, Southmayd EA, Williams NI, De Souza MJ. Strock NCA, et al. Among authors: koltun kj. Int J Sport Nutr Exerc Metab. 2020 Jan 1;30(1):14-24. doi: 10.1123/ijsnem.2019-0199. Int J Sport Nutr Exerc Metab. 2020. PMID: 31887723 Free article.
The purpose of the study was to (a) evaluate the accuracy of RMR prediction methods, (b) determine the relationships with physiological consequences of energy deficiency, and (c) evaluate ratio thresholds in a cross-sectional comparison of ovulatory, amenorrheic, or subcli …
The purpose of the study was to (a) evaluate the accuracy of RMR prediction methods, (b) determine the relationships with physiologic …
RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1- and RAS-driven cancers.
Nichols RJ, Haderk F, Stahlhut C, Schulze CJ, Hemmati G, Wildes D, Tzitzilonis C, Mordec K, Marquez A, Romero J, Hsieh T, Zaman A, Olivas V, McCoach C, Blakely CM, Wang Z, Kiss G, Koltun ES, Gill AL, Singh M, Goldsmith MA, Smith JAM, Bivona TG. Nichols RJ, et al. Among authors: koltun es. Nat Cell Biol. 2018 Sep;20(9):1064-1073. doi: 10.1038/s41556-018-0169-1. Epub 2018 Aug 13. Nat Cell Biol. 2018. PMID: 30104724 Free PMC article.
PTPN2 is associated with Crohn's disease and its expression is regulated by NKX2-3.
Yu W, Hegarty JP, Berg A, Kelly AA, Wang Y, Poritz LS, Franke A, Schreiber S, Koltun WA, Lin Z. Yu W, et al. Among authors: koltun wa. Dis Markers. 2012;32(2):83-91. doi: 10.3233/DMA-2011-0867. Dis Markers. 2012. PMID: 22377701 Free PMC article.
We confirmed this observation by RT-PCR analyses in NKX2-3 knockdown in B cells from IBD patients and human intestinal microvascular endothelial cells (HIMEC). ...A positive correlation was observed between mRNA expression of PTPN2 and NKX2-3 in B cells and in intes …
We confirmed this observation by RT-PCR analyses in NKX2-3 knockdown in B cells from IBD patients and human intestinal microvascular …
29 results