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Critical role of tissue kallikrein in vessel formation and maturation: implications for therapeutic revascularization.
Stone OA, Richer C, Emanueli C, van Weel V, Quax PH, Katare R, Kraenkel N, Campagnolo P, Barcelos LS, Siragusa M, Sala-Newby GB, Baldessari D, Mione M, Vincent MP, Benest AV, Al Haj Zen A, Gonzalez J, Bates DO, Alhenc-Gelas F, Madeddu P. Stone OA, et al. Arterioscler Thromb Vasc Biol. 2009 May;29(5):657-64. doi: 10.1161/ATVBAHA.108.182139. Epub 2009 Jan 22. Arterioscler Thromb Vasc Biol. 2009. PMID: 19164804 Free PMC article.
Recombinant human VEGF165b protein is an effective anti-cancer agent in mice.
Rennel ES, Hamdollah-Zadeh MA, Wheatley ER, Magnussen A, Schüler Y, Kelly SP, Finucane C, Ellison D, Cebe-Suarez S, Ballmer-Hofer K, Mather S, Stewart L, Bates DO, Harper SJ. Rennel ES, et al. Eur J Cancer. 2008 Sep;44(13):1883-94. doi: 10.1016/j.ejca.2008.05.027. Epub 2008 Jul 24. Eur J Cancer. 2008. PMID: 18657413 Free PMC article.
VEGF 165 b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro- and antiangiogenic VEGF-A isoforms has implications for therapy.
Varey AH, Rennel ES, Qiu Y, Bevan HS, Perrin RM, Raffy S, Dixon AR, Paraskeva C, Zaccheo O, Hassan AB, Harper SJ, Bates DO. Varey AH, et al. Br J Cancer. 2008 Apr 22;98(8):1366-79. doi: 10.1038/sj.bjc.6604308. Epub 2008 Mar 18. Br J Cancer. 2008. PMID: 18349829 Free PMC article.