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Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size.
Rosenbloom DIS, Bacchetti P, Stone M, Deng X, Bosch RJ, Richman DD, Siliciano JD, Mellors JW, Deeks SG, Ptak RG, Hoh R, Keating SM, Dimapasoc M, Massanella M, Lai J, Sobolewski MD, Kulpa DA, Busch MP; Reservoir Assay Validation and Evaluation Network (RAVEN) Study Group. Rosenbloom DIS, et al. Among authors: bacchetti p. PLoS Comput Biol. 2019 Apr 12;15(4):e1006849. doi: 10.1371/journal.pcbi.1006849. eCollection 2019 Apr. PLoS Comput Biol. 2019. PMID: 30978183 Free PMC article.
Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral Therapy.
Lee SA, Bacchetti P, Chomont N, Fromentin R, Lewin SR, O'Doherty U, Palmer S, Richman DD, Siliciano JD, Yukl SA, Deeks SG, Burbelo PD. Lee SA, et al. Among authors: bacchetti p. PLoS One. 2016 Aug 2;11(8):e0160192. doi: 10.1371/journal.pone.0160192. eCollection 2016. PLoS One. 2016. PMID: 27483366 Free PMC article.
Assessing the Suitability of Next-Generation Viral Outgrowth Assays to Measure Human Immunodeficiency Virus 1 Latent Reservoir Size.
Stone M, Rosenbloom DIS, Bacchetti P, Deng X, Dimapasoc M, Keating S, Bakkour S, Richman DD, Mellors JW, Deeks SG, Lai J, Beg S, Siliciano JD, Pagliuzza A, Chomont N, Lackman-Smith C, Ptak RG, Busch MP. Stone M, et al. Among authors: bacchetti p. J Infect Dis. 2021 Oct 13;224(7):1209-1218. doi: 10.1093/infdis/jiaa089. J Infect Dis. 2021. PMID: 32147687 Free PMC article.
Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size.
Jain V, Hartogensis W, Bacchetti P, Hunt PW, Hatano H, Sinclair E, Epling L, Lee TH, Busch MP, McCune JM, Pilcher CD, Hecht FM, Deeks SG. Jain V, et al. Among authors: bacchetti p. J Infect Dis. 2013 Oct 15;208(8):1202-11. doi: 10.1093/infdis/jit311. Epub 2013 Jul 12. J Infect Dis. 2013. PMID: 23852127 Free PMC article.
Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers.
Hatano H, Yukl SA, Ferre AL, Graf EH, Somsouk M, Sinclair E, Abdel-Mohsen M, Liegler T, Harvill K, Hoh R, Palmer S, Bacchetti P, Hunt PW, Martin JN, McCune JM, Tracy RP, Busch MP, O'Doherty U, Shacklett BL, Wong JK, Deeks SG. Hatano H, et al. Among authors: bacchetti p. PLoS Pathog. 2013;9(10):e1003691. doi: 10.1371/journal.ppat.1003691. Epub 2013 Oct 10. PLoS Pathog. 2013. PMID: 24130489 Free PMC article. Clinical Trial.
Short-term administration of disulfiram for reversal of latent HIV infection: a phase 2 dose-escalation study.
Elliott JH, McMahon JH, Chang CC, Lee SA, Hartogensis W, Bumpus N, Savic R, Roney J, Hoh R, Solomon A, Piatak M, Gorelick RJ, Lifson J, Bacchetti P, Deeks SG, Lewin SR. Elliott JH, et al. Among authors: bacchetti p. Lancet HIV. 2015 Dec;2(12):e520-9. doi: 10.1016/S2352-3018(15)00226-X. Epub 2015 Nov 17. Lancet HIV. 2015. PMID: 26614966 Free PMC article. Clinical Trial.
Estrogen receptor-1 is a key regulator of HIV-1 latency that imparts gender-specific restrictions on the latent reservoir.
Das B, Dobrowolski C, Luttge B, Valadkhan S, Chomont N, Johnston R, Bacchetti P, Hoh R, Gandhi M, Deeks SG, Scully E, Karn J. Das B, et al. Among authors: bacchetti p. Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7795-E7804. doi: 10.1073/pnas.1803468115. Epub 2018 Jul 30. Proc Natl Acad Sci U S A. 2018. PMID: 30061382 Free PMC article.
347 results