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Year | Number of Results |
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2017 | 1 |
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Page 1
Cysteine depletion induces pancreatic tumor ferroptosis in mice.
Science. 2020 Apr 3;368(6486):85-89. doi: 10.1126/science.aaw9872.
Science. 2020.
PMID: 32241947
Free PMC article.
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis.
Kremer DM, Nelson BS, Lin L, Yarosz EL, Halbrook CJ, Kerk SA, Sajjakulnukit P, Myers A, Thurston G, Hou SW, Carpenter ES, Andren AC, Nwosu ZC, Cusmano N, Wisner S, Mbah NE, Shan M, Das NK, Magnuson B, Little AC, Savani MR, Ramos J, Gao T, Sastra SA, Palermo CF, Badgley MA, Zhang L, Asara JM, McBrayer SK, di Magliano MP, Crawford HC, Shah YM, Olive KP, Lyssiotis CA.
Kremer DM, et al. Among authors: badgley ma.
Nat Commun. 2021 Aug 11;12(1):4860. doi: 10.1038/s41467-021-24859-2.
Nat Commun. 2021.
PMID: 34381026
Free PMC article.
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Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma.
Wasko UN, Jiang J, Curiel-Garcia A, Wang Y, Lee B, Orlen M, Drizyte-Miller K, Menard M, Dilly J, Sastra SA, Palermo CF, Dalton T, Hasselluhn MC, Decker-Farrell AR, Chang S, Jiang L, Wei X, Yang YC, Helland C, Courtney H, Gindin Y, Zhao R, Kemp SB, Clendenin C, Sor R, Vostrejs W, Amparo AA, Hibshman PS, Rees MG, Ronan MM, Roth JA, Bakir B, Badgley MA, Chabot JA, Kluger MD, Manji GA, Quintana E, Wang Z, Smith JAM, Holderfield M, Wildes D, Aguirre AJ, Der CJ, Vonderheide RH, Stanger BZ, Singh M, Olive KP.
Wasko UN, et al. Among authors: badgley ma.
bioRxiv [Preprint]. 2023 Dec 4:2023.12.03.569791. doi: 10.1101/2023.12.03.569791.
bioRxiv. 2023.
PMID: 38105998
Free PMC article.
Preprint.
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Ras-dependent activation of BMAL2 regulates hypoxic metabolism in pancreatic cancer.
Maurer HC, Curiel-Garcia A, Holmstrom S, Laise P, Palermo CF, Sastra SA, Andren A, Li Z, LeLarge T, Sagalovskiy I, Ross DR, Rosario V, Lu K, Ferraiuolo E, Spinosa N, Wong W, Shaw K, Chabot JA, Genkinger J, Hibshoosh H, Manji GA, Iuga A, Schmid RM, Badgley MA, Johnson K, Califano A, Lyssiotis C, Olive KP.
Maurer HC, et al. Among authors: badgley ma.
bioRxiv [Preprint]. 2023 Mar 21:2023.03.19.533333. doi: 10.1101/2023.03.19.533333.
bioRxiv. 2023.
PMID: 36993718
Free PMC article.
Preprint.
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Tumor-selective activity of RAS-GTP inhibition in pancreatic cancer.
Wasko UN, Jiang J, Dalton TC, Curiel-Garcia A, Edwards AC, Wang Y, Lee B, Orlen M, Tian S, Stalnecker CA, Drizyte-Miller K, Menard M, Dilly J, Sastra SA, Palermo CF, Hasselluhn MC, Decker-Farrell AR, Chang S, Jiang L, Wei X, Yang YC, Helland C, Courtney H, Gindin Y, Muonio K, Zhao R, Kemp SB, Clendenin C, Sor R, Vostrejs WP, Hibshman PS, Amparo AM, Hennessey C, Rees MG, Ronan MM, Roth JA, Brodbeck J, Tomassoni L, Bakir B, Socci ND, Herring LE, Barker NK, Wang J, Cleary JM, Wolpin BM, Chabot JA, Kluger MD, Manji GA, Tsai KY, Sekulic M, Lagana SM, Califano A, Quintana E, Wang Z, Smith JAM, Holderfield M, Wildes D, Lowe SW, Badgley MA, Aguirre AJ, Vonderheide RH, Stanger BZ, Baslan T, Der CJ, Singh M, Olive KP.
Wasko UN, et al. Among authors: badgley ma.
Nature. 2024 Apr 8. doi: 10.1038/s41586-024-07379-z. Online ahead of print.
Nature. 2024.
PMID: 38588697
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Adaptive stimulation of macropinocytosis overcomes aspartate limitation in cancer cells under hypoxia.
Garcia-Bermudez J, Badgley MA, Prasad S, Baudrier L, Liu Y, La K, Soula M, Williams RT, Yamaguchi N, Hwang RF, Taylor LJ, de Stanchina E, Rostandy B, Alwaseem H, Molina H, Bar-Sagi D, Birsoy K.
Garcia-Bermudez J, et al. Among authors: badgley ma.
Nat Metab. 2022 Jun;4(6):724-738. doi: 10.1038/s42255-022-00583-z. Epub 2022 Jun 20.
Nat Metab. 2022.
PMID: 35726024
Free PMC article.
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Exploiting cancer's drinking problem: regulation and therapeutic potential of macropinocytosis.
Puccini J, Badgley MA, Bar-Sagi D.
Puccini J, et al. Among authors: badgley ma.
Trends Cancer. 2022 Jan;8(1):54-64. doi: 10.1016/j.trecan.2021.09.004. Epub 2021 Oct 11.
Trends Cancer. 2022.
PMID: 34649835
Free PMC article.
Review.
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Multivalent Small-Molecule Pan-RAS Inhibitors.
Welsch ME, Kaplan A, Chambers JM, Stokes ME, Bos PH, Zask A, Zhang Y, Sanchez-Martin M, Badgley MA, Huang CS, Tran TH, Akkiraju H, Brown LM, Nandakumar R, Cremers S, Yang WS, Tong L, Olive KP, Ferrando A, Stockwell BR.
Welsch ME, et al. Among authors: badgley ma.
Cell. 2017 Feb 23;168(5):878-889.e29. doi: 10.1016/j.cell.2017.02.006.
Cell. 2017.
PMID: 28235199
Free PMC article.
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