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The PPARβ/δ activator GW501516 prevents the down-regulation of AMPK caused by a high-fat diet in liver and amplifies the PGC-1α-Lipin 1-PPARα pathway leading to increased fatty acid oxidation.
Barroso E, Rodríguez-Calvo R, Serrano-Marco L, Astudillo AM, Balsinde J, Palomer X, Vázquez-Carrera M. Barroso E, et al. Among authors: balsinde j. Endocrinology. 2011 May;152(5):1848-59. doi: 10.1210/en.2010-1468. Epub 2011 Mar 1. Endocrinology. 2011. PMID: 21363937 Free article.
Influence of cellular arachidonic acid levels on phospholipid remodeling and CoA-independent transacylase activity in human monocytes and U937 cells.
Astudillo AM, Pérez-Chacón G, Balgoma D, Gil-de-Gómez L, Ruipérez V, Guijas C, Balboa MA, Balsinde J. Astudillo AM, et al. Among authors: balsinde j. Biochim Biophys Acta. 2011 Feb;1811(2):97-103. doi: 10.1016/j.bbalip.2010.11.009. Epub 2010 Dec 8. Biochim Biophys Acta. 2011. PMID: 21145415 Free article.
Dynamics of arachidonic acid mobilization by inflammatory cells.
Astudillo AM, Balgoma D, Balboa MA, Balsinde J. Astudillo AM, et al. Among authors: balsinde j. Biochim Biophys Acta. 2012 Feb;1821(2):249-56. doi: 10.1016/j.bbalip.2011.11.006. Epub 2011 Dec 2. Biochim Biophys Acta. 2012. PMID: 22155285 Free article. Review.
146 results