Basavapathruni A - Search Results

1

Conformational adaptation drives potent, selective and durable inhibition of the human protein methyltransferase DOT1L.

Basavapathruni A, Jin L, Daigle SR, Majer CR, Therkelsen CA, Wigle TJ, Kuntz KW, Chesworth R, Pollock RM, Scott MP, Moyer MP, Richon VM, Copeland RA, Olhava EJ. Basavapathruni A, et al. Chem Biol Drug Des. 2012 Dec;80(6):971-80. doi: 10.1111/cbdd.12050. Epub 2012 Oct 9. Chem Biol Drug Des. 2012. PMID: 22978415

2

Potent inhibition of DOT1L as treatment of MLL-fusion leukemia.

Daigle SR, Olhava EJ, Therkelsen CA, Basavapathruni A, Jin L, Boriack-Sjodin PA, Allain CJ, Klaus CR, Raimondi A, Scott MP, Waters NJ, Chesworth R, Moyer MP, Copeland RA, Richon VM, Pollock RM. Daigle SR, et al. Among authors: basavapathruni a. Blood. 2013 Aug 8;122(6):1017-25. doi: 10.1182/blood-2013-04-497644. Epub 2013 Jun 25. Blood. 2013. PMID: 23801631 Free PMC article.

3

Nonclinical pharmacokinetics and metabolism of EPZ-5676, a novel DOT1L histone methyltransferase inhibitor.

Basavapathruni A, Olhava EJ, Daigle SR, Therkelsen CA, Jin L, Boriack-Sjodin PA, Allain CJ, Klaus CR, Raimondi A, Scott MP, Dovletoglou A, Richon VM, Pollock RM, Copeland RA, Moyer MP, Chesworth R, Pearson PG, Waters NJ. Basavapathruni A, et al. Biopharm Drug Dispos. 2014 May;35(4):237-52. doi: 10.1002/bdd.1889. Epub 2014 Feb 14. Biopharm Drug Dispos. 2014. PMID: 24415392

4

Impact of enzyme concentration and residence time on apparent activity recovery in jump dilution analysis.

Copeland RA, Basavapathruni A, Moyer M, Scott MP. Copeland RA, et al. Among authors: basavapathruni a. Anal Biochem. 2011 Sep 15;416(2):206-10. doi: 10.1016/j.ab.2011.05.029. Epub 2011 May 27. Anal Biochem. 2011. PMID: 21669181

5

Exploring drug delivery for the DOT1L inhibitor pinometostat (EPZ-5676): Subcutaneous administration as an alternative to continuous IV infusion, in the pursuit of an epigenetic target.

Waters NJ, Daigle SR, Rehlaender BN, Basavapathruni A, Campbell CT, Jensen TB, Truitt BF, Olhava EJ, Pollock RM, Stickland KA, Dovletoglou A. Waters NJ, et al. Among authors: basavapathruni a. J Control Release. 2015 Dec 28;220(Pt B):758-65. doi: 10.1016/j.jconrel.2015.09.023. Epub 2015 Sep 15. J Control Release. 2015. PMID: 26385168

6

Characterization of the Enzymatic Activity of SETDB1 and Its 1:1 Complex with ATF7IP.

Basavapathruni A, Gureasko J, Porter Scott M, Hermans W, Godbole A, Leland PA, Boriack-Sjodin PA, Wigle TJ, Copeland RA, Riera TV. Basavapathruni A, et al. Biochemistry. 2016 Mar 22;55(11):1645-51. doi: 10.1021/acs.biochem.5b01202. Epub 2016 Feb 11. Biochemistry. 2016. PMID: 26813693

7

Corrigendum to "Impact of enzyme concentration and residence time on apparent activity recovery in jump dilution analysis" [Anal. Biochem. 416 (2011) 206-210].

Copeland RA, Basavapathruni A, Moyer M, Porter Scott M. Copeland RA, et al. Among authors: basavapathruni a. Anal Biochem. 2022 May 15;645:114637. doi: 10.1016/j.ab.2022.114637. Epub 2022 Mar 3. Anal Biochem. 2022. PMID: 35249722 No abstract available.

8

Developing novel nonnucleoside HIV-1 reverse transcriptase inhibitors: beyond the butterfly.

Basavapathruni A, Anderson KS. Basavapathruni A, et al. Curr Pharm Des. 2006;12(15):1857-65. doi: 10.2174/138161206776873617. Curr Pharm Des. 2006. PMID: 16724952 Review.

9

Mechanistic studies to understand the progressive development of resistance in human immunodeficiency virus type 1 reverse transcriptase to abacavir.

Ray AS, Basavapathruni A, Anderson KS. Ray AS, et al. Among authors: basavapathruni a. J Biol Chem. 2002 Oct 25;277(43):40479-90. doi: 10.1074/jbc.M205303200. Epub 2002 Aug 9. J Biol Chem. 2002. PMID: 12176989 Free article.

10

Probing the molecular mechanisms of AZT drug resistance mediated by HIV-1 reverse transcriptase using a transient kinetic analysis.

Ray AS, Murakami E, Basavapathruni A, Vaccaro JA, Ulrich D, Chu CK, Schinazi RF, Anderson KS. Ray AS, et al. Among authors: basavapathruni a. Biochemistry. 2003 Jul 29;42(29):8831-41. doi: 10.1021/bi034435l. Biochemistry. 2003. PMID: 12873144

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

23 results

Search Page