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Inhibition of human microsomal PGE2 synthase-1 reduces seizure-induced increases of P-glycoprotein expression and activity at the blood-brain barrier.
Soldner ELB, Hartz AMS, Akanuma SI, Pekcec A, Doods H, Kryscio RJ, Hosoya KI, Bauer B. Soldner ELB, et al. Among authors: bauer b. FASEB J. 2019 Dec;33(12):13966-13981. doi: 10.1096/fj.201901460RR. Epub 2019 Oct 22. FASEB J. 2019. PMID: 31638830 Free PMC article.
Our data provide key signaling steps underlying seizure-induced P-gp up-regulation and suggest that mPGES-1 inhibitors could potentially prevent P-gp up-regulation in epilepsy.-Soldner, E. L. B., Hartz, A. M. S., Akanuma, S.-I., Pekcec, A., Doods, H., Kryscio, R. J., Hosoy …
Our data provide key signaling steps underlying seizure-induced P-gp up-regulation and suggest that mPGES-1 inhibitors could potentially pre …
Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo.
Fellner S, Bauer B, Miller DS, Schaffrik M, Fankhänel M, Spruss T, Bernhardt G, Graeff C, Färber L, Gschaidmeier H, Buschauer A, Fricker G. Fellner S, et al. Among authors: bauer b. J Clin Invest. 2002 Nov;110(9):1309-18. doi: 10.1172/JCI15451. J Clin Invest. 2002. PMID: 12417570 Free PMC article.
1,264 results