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Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.
Bleicher L, Aparicio R, Nunes FM, Martinez L, Gomes Dias SM, Figueira AC, Santos MA, Venturelli WH, da Silva R, Donate PM, Neves FA, Simeoni LA, Baxter JD, Webb P, Skaf MS, Polikarpov I. Bleicher L, et al. Among authors: baxter jd. BMC Struct Biol. 2008 Jan 31;8:8. doi: 10.1186/1472-6807-8-8. BMC Struct Biol. 2008. PMID: 18237438 Free PMC article.
Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
Nascimento AS, Dias SM, Nunes FM, Aparício R, Ambrosio AL, Bleicher L, Figueira AC, Santos MA, de Oliveira Neto M, Fischer H, Togashi M, Craievich AF, Garratt RC, Baxter JD, Webb P, Polikarpov I. Nascimento AS, et al. Among authors: baxter jd. J Mol Biol. 2006 Jul 14;360(3):586-98. doi: 10.1016/j.jmb.2006.05.008. Epub 2006 May 19. J Mol Biol. 2006. PMID: 16781732
Gaining ligand selectivity in thyroid hormone receptors via entropy.
Martínez L, Nascimento AS, Nunes FM, Phillips K, Aparicio R, Dias SM, Figueira AC, Lin JH, Nguyen P, Apriletti JW, Neves FA, Baxter JD, Webb P, Skaf MS, Polikarpov I. Martínez L, et al. Among authors: baxter jd. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20717-22. doi: 10.1073/pnas.0911024106. Epub 2009 Nov 19. Proc Natl Acad Sci U S A. 2009. PMID: 19926848 Free PMC article.
Crystallization and preliminary X-ray diffraction studies of isoform alpha1 of the human thyroid hormone receptor ligand-binding domain.
Nunes FM, Aparicio R, Santos MA, Portugal RV, Dias SM, Neves FA, Simeoni LA, Baxter JD, Webb P, Polikarpov I. Nunes FM, et al. Among authors: baxter jd. Acta Crystallogr D Biol Crystallogr. 2004 Oct;60(Pt 10):1867-70. doi: 10.1107/S0907444904017858. Epub 2004 Sep 23. Acta Crystallogr D Biol Crystallogr. 2004. PMID: 15388935
Thyroid hormone response element organization dictates the composition of active receptor.
Velasco LF, Togashi M, Walfish PG, Pessanha RP, Moura FN, Barra GB, Nguyen P, Rebong R, Yuan C, Simeoni LA, Ribeiro RC, Baxter JD, Webb P, Neves FA. Velasco LF, et al. Among authors: baxter jd. J Biol Chem. 2007 Apr 27;282(17):12458-66. doi: 10.1074/jbc.M610700200. Epub 2007 Feb 20. J Biol Chem. 2007. PMID: 17311926 Free article.
Low resolution structures of the retinoid X receptor DNA-binding and ligand-binding domains revealed by synchrotron X-ray solution scattering.
Fischer H, Dias SM, Santos MA, Alves AC, Zanchin N, Craievich AF, Apriletti JW, Baxter JD, Webb P, Neves FA, Ribeiro RC, Polikarpov I. Fischer H, et al. Among authors: baxter jd. J Biol Chem. 2003 May 2;278(18):16030-8. doi: 10.1074/jbc.M206953200. Epub 2003 Jan 17. J Biol Chem. 2003. PMID: 12533536 Free article.
413 results