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A clinically relevant orthotopic xenograft model of ependymoma that maintains the genomic signature of the primary tumor and preserves cancer stem cells in vivo.
Yu L, Baxter PA, Voicu H, Gurusiddappa S, Zhao Y, Adesina A, Man TK, Shu Q, Zhang YJ, Zhao XM, Su JM, Perlaky L, Dauser R, Chintagumpala M, Lau CC, Blaney SM, Rao PH, Leung HC, Li XN. Yu L, et al. Among authors: baxter pa. Neuro Oncol. 2010 Jun;12(6):580-94. doi: 10.1093/neuonc/nop056. Epub 2010 Feb 8. Neuro Oncol. 2010. PMID: 20511191 Free PMC article.
Plasma and cerebrospinal fluid pharmacokinetics of MP470 in non-human primates.
Baxter PA, Thompson PA, McGuffey LM, Gibson BW, Dauser RC, Nuchtern JG, Shi C, Inloes R, Choy G, Redkar S, Blaney SM. Baxter PA, et al. Cancer Chemother Pharmacol. 2011 Apr;67(4):809-12. doi: 10.1007/s00280-010-1380-3. Epub 2010 Jun 19. Cancer Chemother Pharmacol. 2011. PMID: 20563581
A single intravenous injection of oncolytic picornavirus SVV-001 eliminates medulloblastomas in primary tumor-based orthotopic xenograft mouse models.
Yu L, Baxter PA, Zhao X, Liu Z, Wadhwa L, Zhang Y, Su JM, Tan X, Yang J, Adesina A, Perlaky L, Hurwitz M, Idamakanti N, Police SR, Hallenbeck PL, Blaney SM, Chintagumpala M, Hurwitz RL, Li XN. Yu L, et al. Among authors: baxter pa. Neuro Oncol. 2011 Jan;13(1):14-27. doi: 10.1093/neuonc/noq148. Epub 2010 Nov 12. Neuro Oncol. 2011. PMID: 21075780 Free PMC article.
A patient tumor-derived orthotopic xenograft mouse model replicating the group 3 supratentorial primitive neuroectodermal tumor in children.
Liu Z, Zhao X, Wang Y, Mao H, Huang Y, Kogiso M, Qi L, Baxter PA, Man TK, Adesina A, Su JM, Picard D, Ching Ho K, Huang A, Perlaky L, Lau CC, Chintagumpala M, Li XN. Liu Z, et al. Among authors: baxter pa. Neuro Oncol. 2014 Jun;16(6):787-99. doi: 10.1093/neuonc/not244. Epub 2014 Jan 26. Neuro Oncol. 2014. PMID: 24470556 Free PMC article.
Preservation of KIT genotype in a novel pair of patient-derived orthotopic xenograft mouse models of metastatic pediatric CNS germinoma.
Lindsay H, Huang Y, Du Y, Braun FK, Teo WY, Kogiso M, Qi L, Zhang H, Zhao S, Mao H, Lin F, Baxter P, Su JM, Terashima K, Perlaky L, Chintagumpala M, Adesina A, Lau CC, Williams Parsons D, Li XN. Lindsay H, et al. J Neurooncol. 2016 May;128(1):47-56. doi: 10.1007/s11060-016-2098-9. Epub 2016 Mar 8. J Neurooncol. 2016. PMID: 26956263 Free PMC article.
A pediatric brain tumor consortium phase II trial of capecitabine rapidly disintegrating tablets with concomitant radiation therapy in children with newly diagnosed diffuse intrinsic pontine gliomas.
Kilburn LB, Kocak M, Baxter P, Poussaint TY, Paulino AC, McIntyre C, Lemenuel-Diot A, Lopez-Diaz C, Kun L, Chintagumpala M, Su JM, Broniscer A, Baker JN, Hwang EI, Fouladi M, Boyett JM, Blaney SM. Kilburn LB, et al. Pediatr Blood Cancer. 2018 Feb;65(2):10.1002/pbc.26832. doi: 10.1002/pbc.26832. Epub 2017 Nov 1. Pediatr Blood Cancer. 2018. PMID: 29090526 Free PMC article. Clinical Trial.
Xenotransplantation of pediatric low grade gliomas confirms the enrichment of BRAF V600E mutation and preservation of CDKN2A deletion in a novel orthotopic xenograft mouse model of progressive pleomorphic xanthoastrocytoma.
Kogiso M, Qi L, Lindsay H, Huang Y, Zhao X, Liu Z, Braun FK, Du Y, Zhang H, Bae G, Zhao S, Injac SG, Sobieski M, Brunell D, Mehta V, Tran D, Murray J, Baxter PA, Yuan XJ, Su JM, Adesina A, Perlaky L, Chintagumpala M, Parsons DW, Lau CC, Stephan CC, Lu X, Li XN. Kogiso M, et al. Among authors: baxter pa. Oncotarget. 2017 Sep 8;8(50):87455-87471. doi: 10.18632/oncotarget.20713. eCollection 2017 Oct 20. Oncotarget. 2017. PMID: 29152094 Free PMC article.
53 results