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Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens.
Gonçalves E, Segura-Cabrera A, Pacini C, Picco G, Behan FM, Jaaks P, Coker EA, van der Meer D, Barthorpe A, Lightfoot H, Mironenko T, Beck A, Richardson L, Yang W, Lleshi E, Hall J, Tolley C, Hall C, Mali I, Thomas F, Morris J, Leach AR, Lynch JT, Sidders B, Crafter C, Iorio F, Fawell S, Garnett MJ. Gonçalves E, et al. Among authors: beck a. Mol Syst Biol. 2020 Jul;16(7):e9405. doi: 10.15252/msb.20199405. Mol Syst Biol. 2020. PMID: 32627965 Free PMC article.
Effective drug combinations in breast, colon and pancreatic cancer cells.
Jaaks P, Coker EA, Vis DJ, Edwards O, Carpenter EF, Leto SM, Dwane L, Sassi F, Lightfoot H, Barthorpe S, van der Meer D, Yang W, Beck A, Mironenko T, Hall C, Hall J, Mali I, Richardson L, Tolley C, Morris J, Thomas F, Lleshi E, Aben N, Benes CH, Bertotti A, Trusolino L, Wessels L, Garnett MJ. Jaaks P, et al. Among authors: beck a. Nature. 2022 Mar;603(7899):166-173. doi: 10.1038/s41586-022-04437-2. Epub 2022 Feb 23. Nature. 2022. PMID: 35197630 Free PMC article.
Pan-cancer proteomic map of 949 human cell lines.
Gonçalves E, Poulos RC, Cai Z, Barthorpe S, Manda SS, Lucas N, Beck A, Bucio-Noble D, Dausmann M, Hall C, Hecker M, Koh J, Lightfoot H, Mahboob S, Mali I, Morris J, Richardson L, Seneviratne AJ, Shepherd R, Sykes E, Thomas F, Valentini S, Williams SG, Wu Y, Xavier D, MacKenzie KL, Hains PG, Tully B, Robinson PJ, Zhong Q, Garnett MJ, Reddel RR. Gonçalves E, et al. Among authors: beck a. Cancer Cell. 2022 Aug 8;40(8):835-849.e8. doi: 10.1016/j.ccell.2022.06.010. Epub 2022 Jul 14. Cancer Cell. 2022. PMID: 35839778 Free PMC article.
Large-scale Pan-cancer Cell Line Screening Identifies Actionable and Effective Drug Combinations.
Bashi AC, Coker EA, Bulusu KC, Jaaks P, Crafter C, Lightfoot H, Milo M, McCarten K, Jenkins DF, van der Meer D, Lynch JT, Barthorpe S, Andersen CL, Barry ST, Beck A, Cidado J, Gordon JA, Hall C, Hall J, Mali I, Mironenko T, Mongeon K, Morris J, Richardson L, Smith PD, Tavana O, Tolley C, Thomas F, Willis BS, Yang W, O'Connor MJ, McDermott U, Critchlow SE, Drew L, Fawell SE, Mettetal JT, Garnett MJ. Bashi AC, et al. Among authors: beck a. Cancer Discov. 2024 May 1;14(5):846-865. doi: 10.1158/2159-8290.CD-23-0388. Cancer Discov. 2024. PMID: 38456804 Free PMC article.
The Origins and Vulnerabilities of Two Transmissible Cancers in Tasmanian Devils.
Stammnitz MR, Coorens THH, Gori KC, Hayes D, Fu B, Wang J, Martin-Herranz DE, Alexandrov LB, Baez-Ortega A, Barthorpe S, Beck A, Giordano F, Knowles GW, Kwon YM, Hall G, Price S, Pye RJ, Tubio JMC, Siddle HVT, Sohal SS, Woods GM, McDermott U, Yang F, Garnett MJ, Ning Z, Murchison EP. Stammnitz MR, et al. Among authors: beck a. Cancer Cell. 2018 Apr 9;33(4):607-619.e15. doi: 10.1016/j.ccell.2018.03.013. Cancer Cell. 2018. PMID: 29634948 Free PMC article.
Novel Measurement of the Neutron Magnetic Form Factor from A=3 Mirror Nuclei.
Santiesteban SN, Li S, Abrams D, Alsalmi S, Androic D, Aniol K, Arrington J, Averett T, Ayerbe Gayoso C, Bane J, Barcus S, Barrow J, Beck A, Bellini V, Bhatt H, Bhetuwal D, Biswas D, Camsonne A, Castellanos J, Chen J, Chen JP, Chrisman D, Christy ME, Clarke C, Covrig S, Cruz-Torres R, Day D, Dutta D, Fuchey E, Gal C, Garibaldi F, Gautam TN, Gogami T, Gomez J, Guèye P, Hague TJ, Hansen JO, Hauenstein F, Henry W, Higinbotham DW, Holt RJ, Hyde C, Itabashi K, Kaneta M, Karki A, Katramatou AT, Keppel CE, King PM, Kurbany L, Kutz T, Lashley-Colthirst N, Li WB, Liu H, Liyanage N, Long E, Lovato A, Mammei J, Markowitz P, McClellan RE, Meddi F, Meekins D, Michaels R, Mihovilovič M, Moyer A, Nagao S, Nguyen D, Nycz M, Olson M, Ou L, Owen V, Palatchi C, Pandey B, Papadopoulou A, Park S, Petkovic T, Premathilake S, Punjabi V, Ransome RD, Reimer PE, Reinhold J, Riordan S, Rocco N, Rodriguez VM, Schmidt A, Schmookler B, Segarra EP, Shahinyan A, Širca S, Slifer K, Solvignon P, Su T, Suleiman R, Tang L, Tian Y, Tireman W, Tortorici F, Toyama Y, Uehara K, Urciuoli GM, Votaw D, Williamson J, Wojtsekhowski B, Wood S, Ye ZH, Zhang J, Zheng X; Jefferson Lab Hall A Collaboration. Santiesteban SN, et al. Among authors: beck a. Phys Rev Lett. 2024 Apr 19;132(16):162501. doi: 10.1103/PhysRevLett.132.162501. Phys Rev Lett. 2024. PMID: 38701469
3,532 results