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ARID1A Regulates Transcription and the Epigenetic Landscape via POLE and DMAP1 while ARID1A Deficiency or Pharmacological Inhibition Sensitizes Germ Cell Tumor Cells to ATR Inhibition.
Kurz L, Miklyaeva A, Skowron MA, Overbeck N, Poschmann G, Becker T, Eul K, Kurz T, Schönberger S, Calaminus G, Stühler K, Dykhuizen E, Albers P, Nettersheim D. Kurz L, et al. Among authors: becker t. Cancers (Basel). 2020 Apr 7;12(4):905. doi: 10.3390/cancers12040905. Cancers (Basel). 2020. PMID: 32272809 Free PMC article.
CDK4/6 inhibition presents as a therapeutic option for paediatric and adult germ cell tumours and induces cell cycle arrest and apoptosis via canonical and non-canonical mechanisms.
Skowron MA, Vermeulen M, Winkelhausen A, Becker TK, Bremmer F, Petzsch P, Schönberger S, Calaminus G, Köhrer K, Albers P, Nettersheim D. Skowron MA, et al. Br J Cancer. 2020 Aug;123(3):378-391. doi: 10.1038/s41416-020-0891-x. Epub 2020 May 18. Br J Cancer. 2020. PMID: 32418994 Free PMC article.
The signal transducer CD24 suppresses the germ cell program and promotes an ectodermal rather than mesodermal cell fate in embryonal carcinomas.
Skowron MA, Becker TK, Kurz L, Jostes S, Bremmer F, Fronhoffs F, Funke K, Wakileh GA, Müller MR, Burmeister A, Lenz T, Stefanski A, Stühler K, Petzsch P, Köhrer K, Altevogt P, Albers P, Kristiansen G, Schorle H, Nettersheim D. Skowron MA, et al. Among authors: becker tk. Mol Oncol. 2022 Feb;16(4):982-1008. doi: 10.1002/1878-0261.13066. Epub 2021 Aug 2. Mol Oncol. 2022. PMID: 34293822 Free PMC article.
C9ORF72 deficiency results in neurodegeneration in the zebrafish retina.
Jaroszynska N, Salzinger A, Tsarouchas TM, Becker CG, Becker T, Lyons DA, MacDonald RB, Keatinge M. Jaroszynska N, et al. Among authors: becker t. J Neurosci. 2024 Apr 24:e2128232024. doi: 10.1523/JNEUROSCI.2128-23.2024. Online ahead of print. J Neurosci. 2024. PMID: 38658168
Mesoporous Silica as an Alternative Vehicle to Overcome Solubility Limitations.
Becker T, Heitkötter J, Krome AK, Schiefer A, Pfarr K, Ehrens A, Grosse M, Sandargo B, Stammberger I, Stadler M, Hübner MP, Kehraus S, Hoerauf A, Wagner KG. Becker T, et al. Pharmaceutics. 2024 Mar 12;16(3):386. doi: 10.3390/pharmaceutics16030386. Pharmaceutics. 2024. PMID: 38543280 Free PMC article.
2,374 results