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Page 1
CaMKII exacerbates heart failure progression by activating class I HDACs.
Zhang M, Yang X, Zimmerman RJ, Wang Q, Ross MA, Granger JM, Luczak ED, Bedja D, Jiang H, Feng N. Zhang M, et al. Among authors: bedja d. J Mol Cell Cardiol. 2020 Dec;149:73-81. doi: 10.1016/j.yjmcc.2020.09.007. Epub 2020 Sep 22. J Mol Cell Cardiol. 2020. PMID: 32971072 Free PMC article.
Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice.
Takimoto E, Koitabashi N, Hsu S, Ketner EA, Zhang M, Nagayama T, Bedja D, Gabrielson KL, Blanton R, Siderovski DP, Mendelsohn ME, Kass DA. Takimoto E, et al. Among authors: bedja d. J Clin Invest. 2009 Feb;119(2):408-20. doi: 10.1172/JCI35620. Epub 2009 Jan 5. J Clin Invest. 2009. PMID: 19127022 Free PMC article.
Sildenafil stops progressive chamber, cellular, and molecular remodeling and improves calcium handling and function in hearts with pre-existing advanced hypertrophy caused by pressure overload.
Nagayama T, Hsu S, Zhang M, Koitabashi N, Bedja D, Gabrielson KL, Takimoto E, Kass DA. Nagayama T, et al. Among authors: bedja d. J Am Coll Cardiol. 2009 Jan 13;53(2):207-15. doi: 10.1016/j.jacc.2008.08.069. J Am Coll Cardiol. 2009. PMID: 19130990 Free PMC article.
Adverse ventricular remodeling and exacerbated NOS uncoupling from pressure-overload in mice lacking the beta3-adrenoreceptor.
Moens AL, Leyton-Mange JS, Niu X, Yang R, Cingolani O, Arkenbout EK, Champion HC, Bedja D, Gabrielson KL, Chen J, Xia Y, Hale AB, Channon KM, Halushka MK, Barker N, Wuyts FL, Kaminski PM, Wolin MS, Kass DA, Barouch LA. Moens AL, et al. Among authors: bedja d. J Mol Cell Cardiol. 2009 Nov;47(5):576-85. doi: 10.1016/j.yjmcc.2009.06.005. Epub 2009 Sep 18. J Mol Cell Cardiol. 2009. PMID: 19766235 Free PMC article.
Monoamine oxidase A-mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload.
Kaludercic N, Takimoto E, Nagayama T, Feng N, Lai EW, Bedja D, Chen K, Gabrielson KL, Blakely RD, Shih JC, Pacak K, Kass DA, Di Lisa F, Paolocci N. Kaludercic N, et al. Among authors: bedja d. Circ Res. 2010 Jan 8;106(1):193-202. doi: 10.1161/CIRCRESAHA.109.198366. Epub 2009 Nov 12. Circ Res. 2010. PMID: 19910579 Free PMC article.
106 results