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An acetylation site in the middle domain of Hsp90 regulates chaperone function.
Scroggins BT, Robzyk K, Wang D, Marcu MG, Tsutsumi S, Beebe K, Cotter RJ, Felts S, Toft D, Karnitz L, Rosen N, Neckers L. Scroggins BT, et al. Among authors: beebe k. Mol Cell. 2007 Jan 12;25(1):151-9. doi: 10.1016/j.molcel.2006.12.008. Mol Cell. 2007. PMID: 17218278 Free PMC article.
Impact of heat-shock protein 90 on cancer metastasis.
Tsutsumi S, Beebe K, Neckers L. Tsutsumi S, et al. Among authors: beebe k. Future Oncol. 2009 Jun;5(5):679-88. doi: 10.2217/fon.09.30. Future Oncol. 2009. PMID: 19519207 Free PMC article. Review.
Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function.
Mollapour M, Tsutsumi S, Donnelly AC, Beebe K, Tokita MJ, Lee MJ, Lee S, Morra G, Bourboulia D, Scroggins BT, Colombo G, Blagg BS, Panaretou B, Stetler-Stevenson WG, Trepel JB, Piper PW, Prodromou C, Pearl LH, Neckers L. Mollapour M, et al. Among authors: beebe k. Mol Cell. 2010 Feb 12;37(3):333-43. doi: 10.1016/j.molcel.2010.01.005. Mol Cell. 2010. PMID: 20159553 Free PMC article.
Asymmetric Hsp90 N domain SUMOylation recruits Aha1 and ATP-competitive inhibitors.
Mollapour M, Bourboulia D, Beebe K, Woodford MR, Polier S, Hoang A, Chelluri R, Li Y, Guo A, Lee MJ, Fotooh-Abadi E, Khan S, Prince T, Miyajima N, Yoshida S, Tsutsumi S, Xu W, Panaretou B, Stetler-Stevenson WG, Bratslavsky G, Trepel JB, Prodromou C, Neckers L. Mollapour M, et al. Among authors: beebe k. Mol Cell. 2014 Jan 23;53(2):317-29. doi: 10.1016/j.molcel.2013.12.007. Mol Cell. 2014. PMID: 24462205 Free PMC article.
Combined HSP90 and kinase inhibitor therapy: Insights from The Cancer Genome Atlas.
Schwartz H, Scroggins B, Zuehlke A, Kijima T, Beebe K, Mishra A, Neckers L, Prince T. Schwartz H, et al. Among authors: beebe k. Cell Stress Chaperones. 2015 Sep;20(5):729-41. doi: 10.1007/s12192-015-0604-1. Epub 2015 Jun 13. Cell Stress Chaperones. 2015. PMID: 26070366 Free PMC article. Review.
205 results