Begthel H - Search Results

1

Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis.

Huch M, Bonfanti P, Boj SF, Sato T, Loomans CJ, van de Wetering M, Sojoodi M, Li VS, Schuijers J, Gracanin A, Ringnalda F, Begthel H, Hamer K, Mulder J, van Es JH, de Koning E, Vries RG, Heimberg H, Clevers H. Huch M, et al. Among authors: begthel h. EMBO J. 2013 Oct 16;32(20):2708-21. doi: 10.1038/emboj.2013.204. Epub 2013 Sep 17. EMBO J. 2013. PMID: 24045232 Free PMC article.

2

Canonical Wnt signals are essential for homeostasis of the intestinal epithelium.

Pinto D, Gregorieff A, Begthel H, Clevers H. Pinto D, et al. Among authors: begthel h. Genes Dev. 2003 Jul 15;17(14):1709-13. doi: 10.1101/gad.267103. Genes Dev. 2003. PMID: 12865297 Free PMC article.

3

The Wnt/beta-catenin pathway regulates cardiac valve formation.

Hurlstone AF, Haramis AP, Wienholds E, Begthel H, Korving J, Van Eeden F, Cuppen E, Zivkovic D, Plasterk RH, Clevers H. Hurlstone AF, et al. Among authors: begthel h. Nature. 2003 Oct 9;425(6958):633-7. doi: 10.1038/nature02028. Nature. 2003. PMID: 14534590 Free article.

4

De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine.

Haramis AP, Begthel H, van den Born M, van Es J, Jonkheer S, Offerhaus GJ, Clevers H. Haramis AP, et al. Among authors: begthel h. Science. 2004 Mar 12;303(5664):1684-6. doi: 10.1126/science.1093587. Science. 2004. PMID: 15017003

5

Wnt signalling induces maturation of Paneth cells in intestinal crypts.

van Es JH, Jay P, Gregorieff A, van Gijn ME, Jonkheer S, Hatzis P, Thiele A, van den Born M, Begthel H, Brabletz T, Taketo MM, Clevers H. van Es JH, et al. Among authors: begthel h. Nat Cell Biol. 2005 Apr;7(4):381-6. doi: 10.1038/ncb1240. Epub 2005 Mar 20. Nat Cell Biol. 2005. PMID: 15778706

6

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells.

van Es JH, van Gijn ME, Riccio O, van den Born M, Vooijs M, Begthel H, Cozijnsen M, Robine S, Winton DJ, Radtke F, Clevers H. van Es JH, et al. Among authors: begthel h. Nature. 2005 Jun 16;435(7044):959-63. doi: 10.1038/nature03659. Nature. 2005. PMID: 15959515

7

EphB receptor activity suppresses colorectal cancer progression.

Batlle E, Bacani J, Begthel H, Jonkheer S, Gregorieff A, van de Born M, Malats N, Sancho E, Boon E, Pawson T, Gallinger S, Pals S, Clevers H. Batlle E, et al. Among authors: begthel h. Nature. 2005 Jun 23;435(7045):1126-30. doi: 10.1038/nature03626. Nature. 2005. PMID: 15973414

8

Expression pattern of Wnt signaling components in the adult intestine.

Gregorieff A, Pinto D, Begthel H, Destrée O, Kielman M, Clevers H. Gregorieff A, et al. Among authors: begthel h. Gastroenterology. 2005 Aug;129(2):626-38. doi: 10.1016/j.gastro.2005.06.007. Gastroenterology. 2005. PMID: 16083717

9

Adenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia.

Haramis AP, Hurlstone A, van der Velden Y, Begthel H, van den Born M, Offerhaus GJ, Clevers HC. Haramis AP, et al. Among authors: begthel h. EMBO Rep. 2006 Apr;7(4):444-9. doi: 10.1038/sj.embor.7400638. Epub 2006 Jan 27. EMBO Rep. 2006. PMID: 16439994 Free PMC article.

10

Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc.

Muncan V, Sansom OJ, Tertoolen L, Phesse TJ, Begthel H, Sancho E, Cole AM, Gregorieff A, de Alboran IM, Clevers H, Clarke AR. Muncan V, et al. Among authors: begthel h. Mol Cell Biol. 2006 Nov;26(22):8418-26. doi: 10.1128/MCB.00821-06. Epub 2006 Sep 5. Mol Cell Biol. 2006. PMID: 16954380 Free PMC article.

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