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A modular platform for targeted RNAi therapeutics.
Kedmi R, Veiga N, Ramishetti S, Goldsmith M, Rosenblum D, Dammes N, Hazan-Halevy I, Nahary L, Leviatan-Ben-Arye S, Harlev M, Behlke M, Benhar I, Lieberman J, Peer D. Kedmi R, et al. Among authors: behlke m. Nat Nanotechnol. 2018 Mar;13(3):214-219. doi: 10.1038/s41565-017-0043-5. Epub 2018 Jan 29. Nat Nanotechnol. 2018. PMID: 29379205
CRISPR-Cas9 genome editing using targeted lipid nanoparticles for cancer therapy.
Rosenblum D, Gutkin A, Kedmi R, Ramishetti S, Veiga N, Jacobi AM, Schubert MS, Friedmann-Morvinski D, Cohen ZR, Behlke MA, Lieberman J, Peer D. Rosenblum D, et al. Among authors: behlke ma. Sci Adv. 2020 Nov 18;6(47):eabc9450. doi: 10.1126/sciadv.abc9450. Print 2020 Nov. Sci Adv. 2020. PMID: 33208369 Free PMC article.
Progress toward in vivo use of siRNAs-II.
Rettig GR, Behlke MA. Rettig GR, et al. Mol Ther. 2012 Mar;20(3):483-512. doi: 10.1038/mt.2011.263. Epub 2011 Dec 20. Mol Ther. 2012. PMID: 22186795 Free PMC article. Review.
AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines.
Zhang L, Zuris JA, Viswanathan R, Edelstein JN, Turk R, Thommandru B, Rube HT, Glenn SE, Collingwood MA, Bode NM, Beaudoin SF, Lele S, Scott SN, Wasko KM, Sexton S, Borges CM, Schubert MS, Kurgan GL, McNeill MS, Fernandez CA, Myer VE, Morgan RA, Behlke MA, Vakulskas CA. Zhang L, et al. Among authors: behlke ma. Nat Commun. 2021 Jun 23;12(1):3908. doi: 10.1038/s41467-021-24017-8. Nat Commun. 2021. PMID: 34162850 Free PMC article.
Progress towards in vivo use of siRNAs.
Behlke MA. Behlke MA. Mol Ther. 2006 Apr;13(4):644-70. doi: 10.1016/j.ymthe.2006.01.001. Epub 2006 Feb 14. Mol Ther. 2006. PMID: 16481219 Free PMC article. Review.
Design of active small interfering RNAs.
Peek AS, Behlke MA. Peek AS, et al. Curr Opin Mol Ther. 2007 Apr;9(2):110-8. Curr Opin Mol Ther. 2007. PMID: 17458163 Review.
153 results