Behlke MA - Search Results

1

Knockdown of β-catenin with dicer-substrate siRNAs reduces liver tumor burden in vivo.

Dudek H, Wong DH, Arvan R, Shah A, Wortham K, Ying B, Diwanji R, Zhou W, Holmes B, Yang H, Cyr WA, Zhou Y, Shah A, Farkiwala R, Lee M, Li Y, Rettig GR, Collingwood MA, Basu SK, Behlke MA, Brown BD. Dudek H, et al. Among authors: behlke ma. Mol Ther. 2014 Jan;22(1):92-101. doi: 10.1038/mt.2013.233. Epub 2013 Oct 3. Mol Ther. 2014. PMID: 24089139 Free PMC article.

2

Progress toward in vivo use of siRNAs-II.

Rettig GR, Behlke MA. Rettig GR, et al. Among authors: behlke ma. Mol Ther. 2012 Mar;20(3):483-512. doi: 10.1038/mt.2011.263. Epub 2011 Dec 20. Mol Ther. 2012. PMID: 22186795 Free PMC article. Review.

3

Functional polarity is introduced by Dicer processing of short substrate RNAs.

Rose SD, Kim DH, Amarzguioui M, Heidel JD, Collingwood MA, Davis ME, Rossi JJ, Behlke MA. Rose SD, et al. Among authors: behlke ma. Nucleic Acids Res. 2005 Jul 26;33(13):4140-56. doi: 10.1093/nar/gki732. Print 2005. Nucleic Acids Res. 2005. PMID: 16049023 Free PMC article.

4

Central delivery of Dicer-substrate siRNA: a direct application for pain research.

Doré-Savard L, Roussy G, Dansereau MA, Collingwood MA, Lennox KA, Rose SD, Beaudet N, Behlke MA, Sarret P. Doré-Savard L, et al. Among authors: behlke ma. Mol Ther. 2008 Jul;16(7):1331-9. doi: 10.1038/mt.2008.98. Epub 2008 Jun 3. Mol Ther. 2008. PMID: 18523447 Free article.

5

Chemical modification patterns compatible with high potency dicer-substrate small interfering RNAs.

Collingwood MA, Rose SD, Huang L, Hillier C, Amarzguioui M, Wiiger MT, Soifer HS, Rossi JJ, Behlke MA. Collingwood MA, et al. Among authors: behlke ma. Oligonucleotides. 2008 Jun;18(2):187-200. doi: 10.1089/oli.2008.0123. Oligonucleotides. 2008. PMID: 18637735 Free PMC article.

6

Progress towards in vivo use of siRNAs.

Behlke MA. Behlke MA. Mol Ther. 2006 Apr;13(4):644-70. doi: 10.1016/j.ymthe.2006.01.001. Epub 2006 Feb 14. Mol Ther. 2006. PMID: 16481219 Free PMC article. Review.

7

Increasing CRISPR Efficiency and Measuring Its Specificity in HSPCs Using a Clinically Relevant System.

Shapiro J, Iancu O, Jacobi AM, McNeill MS, Turk R, Rettig GR, Amit I, Tovin-Recht A, Yakhini Z, Behlke MA, Hendel A. Shapiro J, et al. Among authors: behlke ma. Mol Ther Methods Clin Dev. 2020 May 4;17:1097-1107. doi: 10.1016/j.omtm.2020.04.027. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2020. PMID: 32478125 Free PMC article.

8

Simplified CRISPR tools for efficient genome editing and streamlined protocols for their delivery into mammalian cells and mouse zygotes.

Jacobi AM, Rettig GR, Turk R, Collingwood MA, Zeiner SA, Quadros RM, Harms DW, Bonthuis PJ, Gregg C, Ohtsuka M, Gurumurthy CB, Behlke MA. Jacobi AM, et al. Among authors: behlke ma. Methods. 2017 May 15;121-122:16-28. doi: 10.1016/j.ymeth.2017.03.021. Epub 2017 Mar 27. Methods. 2017. PMID: 28351759 Free PMC article.

9

A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs.

Soifer HS, Sano M, Sakurai K, Chomchan P, Saetrom P, Sherman MA, Collingwood MA, Behlke MA, Rossi JJ. Soifer HS, et al. Among authors: behlke ma. Nucleic Acids Res. 2008 Nov;36(20):6511-22. doi: 10.1093/nar/gkn687. Epub 2008 Oct 15. Nucleic Acids Res. 2008. PMID: 18927112 Free PMC article.

10

CRISPAltRations: a validated cloud-based approach for interrogation of double-strand break repair mediated by CRISPR genome editing.

Kurgan G, Turk R, Li H, Roberts N, Rettig GR, Jacobi AM, Tso L, Sturgeon M, Mertens M, Noten R, Florus K, Behlke MA, Wang Y, McNeill MS. Kurgan G, et al. Among authors: behlke ma. Mol Ther Methods Clin Dev. 2021 Apr 2;21:478-491. doi: 10.1016/j.omtm.2021.03.024. eCollection 2021 Jun 11. Mol Ther Methods Clin Dev. 2021. PMID: 33981780 Free PMC article.

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