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Page 1
The epigenomics of schizophrenia, in the mouse.
Javidfar B, Park R, Kassim BS, Bicks LK, Akbarian S. Javidfar B, et al. Am J Med Genet B Neuropsychiatr Genet. 2017 Sep;174(6):631-640. doi: 10.1002/ajmg.b.32566. Epub 2017 Jul 12. Am J Med Genet B Neuropsychiatr Genet. 2017. PMID: 28699694 Free PMC article. Review.
HIV integration in the human brain is linked to microglial activation and 3D genome remodeling.
Plaza-Jennings AL, Valada A, O'Shea C, Iskhakova M, Hu B, Javidfar B, Ben Hutta G, Lambert TY, Murray J, Kassim B, Chandrasekaran S, Chen BK, Morgello S, Won H, Akbarian S. Plaza-Jennings AL, et al. Among authors: javidfar b. Mol Cell. 2022 Dec 15;82(24):4647-4663.e8. doi: 10.1016/j.molcel.2022.11.016. Mol Cell. 2022. PMID: 36525955 Free PMC article.
HIV-1 infection of genetically engineered iPSC-derived central nervous system-engrafted microglia in a humanized mouse model.
Min AK, Javidfar B, Missall R, Doanman D, Durens M, Vil SS, Masih Z, Graziani M, Mordelt A, Marro S, de Witte L, Chen BK, Swartz TH, Akbarian S. Min AK, et al. Among authors: javidfar b. bioRxiv [Preprint]. 2023 Apr 27:2023.04.26.538461. doi: 10.1101/2023.04.26.538461. bioRxiv. 2023. PMID: 37162838 Free PMC article. Updated. Preprint.
R-loop landscapes in the developing human brain are linked to neural differentiation and cell-type specific transcription.
LaMarca EA, Saito A, Plaza-Jennings A, Espeso-Gil S, Hellmich A, Fernando MB, Javidfar B, Liao W, Estill M, Townsley K, Florio A, Ethridge JE, Do C, Tycko B, Shen L, Kamiya A, Tsankova NM, Brennand KJ, Akbarian S. LaMarca EA, et al. Among authors: javidfar b. bioRxiv [Preprint]. 2023 Jul 18:2023.07.18.549494. doi: 10.1101/2023.07.18.549494. bioRxiv. 2023. PMID: 37503149 Free PMC article. Preprint.
Neuron-specific chromosomal megadomain organization is adaptive to recent retrotransposon expansions.
Chandrasekaran S, Espeso-Gil S, Loh YE, Javidfar B, Kassim B, Zhu Y, Zhang Y, Dong Y, Bicks LK, Li H, Rajarajan P, Peter CJ, Sun D, Agullo-Pascual E, Iskhakova M, Estill M, Lesch BJ, Shen L, Jiang Y, Akbarian S. Chandrasekaran S, et al. Among authors: javidfar b. Nat Commun. 2021 Dec 13;12(1):7243. doi: 10.1038/s41467-021-26862-z. Nat Commun. 2021. PMID: 34903713 Free PMC article.
Targeting histone demethylase LSD1 for treatment of deficits in autism mouse models.
Rapanelli M, Williams JB, Ma K, Yang F, Zhong P, Patel R, Kumar M, Qin L, Rein B, Wang ZJ, Kassim B, Javidfar B, Couto L, Akbarian S, Yan Z. Rapanelli M, et al. Among authors: javidfar b. Mol Psychiatry. 2022 Aug;27(8):3355-3366. doi: 10.1038/s41380-022-01508-8. Epub 2022 Mar 16. Mol Psychiatry. 2022. PMID: 35296809 Free PMC article.
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk.
Rajarajan P, Borrman T, Liao W, Schrode N, Flaherty E, Casiño C, Powell S, Yashaswini C, LaMarca EA, Kassim B, Javidfar B, Espeso-Gil S, Li A, Won H, Geschwind DH, Ho SM, MacDonald M, Hoffman GE, Roussos P, Zhang B, Hahn CG, Weng Z, Brennand KJ, Akbarian S. Rajarajan P, et al. Among authors: javidfar b. Science. 2018 Dec 14;362(6420):eaat4311. doi: 10.1126/science.aat4311. Science. 2018. PMID: 30545851 Free PMC article.
Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex.
Mitchell AC, Javidfar B, Bicks LK, Neve R, Garbett K, Lander SS, Mirnics K, Morishita H, Wood MA, Jiang Y, Gaisler-Salomon I, Akbarian S. Mitchell AC, et al. Among authors: javidfar b. Nat Commun. 2016 Sep 6;7:12743. doi: 10.1038/ncomms12743. Nat Commun. 2016. PMID: 27597321 Free PMC article.
18 results