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Page 1
Targeting PARP11 to avert immunosuppression and improve CAR T therapy in solid tumors.
Zhang H, Yu P, Tomar VS, Chen X, Atherton MJ, Lu Z, Zhang HG, Li S, Ortiz A, Gui J, Leu NA, Yan F, Blanco A, Meyer-Ficca ML, Meyer RG, Beiting DP, Li J, Nunez-Cruz S, O'Connor RS, Johnson LR, Minn AJ, George SS, Koumenis C, Diehl JA, Milone MC, Zheng H, Fuchs SY. Zhang H, et al. Among authors: beiting dp. Nat Cancer. 2022 Jul;3(7):808-820. doi: 10.1038/s43018-022-00383-0. Epub 2022 May 30. Nat Cancer. 2022. PMID: 35637402 Free PMC article.
NKG2D promotes CD8 T cell-mediated cytotoxicity and is associated with treatment failure in human cutaneous leishmaniasis.
Sacramento LA, Farias Amorim C, Campos TM, Saldanha M, Arruda S, Carvalho LP, Beiting DP, Carvalho EM, Novais FO, Scott P. Sacramento LA, et al. Among authors: beiting dp. PLoS Negl Trop Dis. 2023 Aug 21;17(8):e0011552. doi: 10.1371/journal.pntd.0011552. eCollection 2023 Aug. PLoS Negl Trop Dis. 2023. PMID: 37603573 Free PMC article.
Selective whole-genome amplification reveals population genetics of Leishmania braziliensis directly from patient skin biopsies.
Pilling OA, Reis-Cunha JL, Grace CA, Berry ASF, Mitchell MW, Yu JA, Malekshahi CR, Krespan E, Go CK, Lombana C, Song YS, Amorim CF, Lago AS, Carvalho LP, Carvalho EM, Brisson D, Scott P, Jeffares DC, Beiting DP. Pilling OA, et al. Among authors: beiting dp. PLoS Pathog. 2023 Mar 20;19(3):e1011230. doi: 10.1371/journal.ppat.1011230. eCollection 2023 Mar. PLoS Pathog. 2023. PMID: 36940219 Free PMC article.
Type I Interferons Control Proliferation and Function of the Intestinal Epithelium.
Katlinskaya YV, Katlinski KV, Lasri A, Li N, Beiting DP, Durham AC, Yang T, Pikarsky E, Lengner CJ, Johnson FB, Ben-Neriah Y, Fuchs SY. Katlinskaya YV, et al. Among authors: beiting dp. Mol Cell Biol. 2016 Jan 25;36(7):1124-35. doi: 10.1128/MCB.00988-15. Mol Cell Biol. 2016. PMID: 26811327 Free PMC article.
Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression.
Katlinskaya YV, Katlinski KV, Yu Q, Ortiz A, Beiting DP, Brice A, Davar D, Sanders C, Kirkwood JM, Rui H, Xu X, Koumenis C, Diehl JA, Fuchs SY. Katlinskaya YV, et al. Among authors: beiting dp. Cell Rep. 2016 Apr 5;15(1):171-180. doi: 10.1016/j.celrep.2016.03.006. Epub 2016 Mar 24. Cell Rep. 2016. PMID: 27052162 Free PMC article.
Inactivation of Interferon Receptor Promotes the Establishment of Immune Privileged Tumor Microenvironment.
Katlinski KV, Gui J, Katlinskaya YV, Ortiz A, Chakraborty R, Bhattacharya S, Carbone CJ, Beiting DP, Girondo MA, Peck AR, Puré E, Chatterji P, Rustgi AK, Diehl JA, Koumenis C, Rui H, Fuchs SY. Katlinski KV, et al. Among authors: beiting dp. Cancer Cell. 2017 Feb 13;31(2):194-207. doi: 10.1016/j.ccell.2017.01.004. Cancer Cell. 2017. PMID: 28196594 Free PMC article.
Regulation of intercellular biomolecule transfer-driven tumor angiogenesis and responses to anticancer therapies.
Lu Z, Ortiz A, Verginadis II, Peck AR, Zahedi F, Cho C, Yu P, DeRita RM, Zhang H, Kubanoff R, Sun Y, Yaspan AT, Krespan E, Beiting DP, Radaelli E, Ryeom SW, Diehl JA, Rui H, Koumenis C, Fuchs SY. Lu Z, et al. Among authors: beiting dp. J Clin Invest. 2021 May 17;131(10):e144225. doi: 10.1172/JCI144225. J Clin Invest. 2021. PMID: 33998600 Free PMC article.
Activation of p38α stress-activated protein kinase drives the formation of the pre-metastatic niche in the lungs.
Gui J, Zahedi F, Ortiz A, Cho C, Katlinski KV, Alicea-Torres K, Li J, Todd L, Zhang H, Beiting DP, Sander C, Kirkwood JM, Snow BE, Wakeham AC, Mak TW, Diehl JA, Koumenis C, Ryeom SW, Stanger BZ, Puré E, Gabrilovich DI, Fuchs SY. Gui J, et al. Among authors: beiting dp. Nat Cancer. 2020 Jun;1(6):603-619. doi: 10.1038/s43018-020-0064-0. Epub 2020 May 25. Nat Cancer. 2020. PMID: 34124690 Free PMC article.
ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes.
Lu Z, McBrearty N, Chen J, Tomar VS, Zhang H, De Rosa G, Tan A, Weljie AM, Beiting DP, Miao Z, George SS, Berger A, Saggu G, Diehl JA, Koumenis C, Fuchs SY. Lu Z, et al. Among authors: beiting dp. Cell Metab. 2022 Sep 6;34(9):1342-1358.e7. doi: 10.1016/j.cmet.2022.08.007. Cell Metab. 2022. PMID: 36070682 Free PMC article.
95 results