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2022 2
2023 8
2024 2

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Page 1
Serine synthesis via reversed SHMT2 activity drives glycine depletion and acetaminophen hepatotoxicity in MASLD.
Ghrayeb A, Finney AC, Agranovich B, Peled D, Anand SK, McKinney MP, Sarji M, Yang D, Weissman N, Drucker S, Fernandes SI, Fernández-García J, Mahan K, Abassi Z, Tan L, Lorenzi PL, Traylor J, Zhang J, Abramovich I, Chen YE, Rom O, Mor I, Gottlieb E. Ghrayeb A, et al. Among authors: agranovich b. Cell Metab. 2024 Jan 2;36(1):116-129.e7. doi: 10.1016/j.cmet.2023.12.013. Cell Metab. 2024. PMID: 38171331
Mapping the metabolic reprogramming induced by sodium-glucose cotransporter 2 inhibition.
Kogot-Levin A, Riahi Y, Abramovich I, Mosenzon O, Agranovich B, Kadosh L, Ben-Haroush Schyr R, Kleiman D, Hinden L, Cerasi E, Ben-Zvi D, Bernal-Mizrachi E, Tam J, Gottlieb E, Leibowitz G. Kogot-Levin A, et al. Among authors: agranovich b. JCI Insight. 2023 Apr 10;8(7):e164296. doi: 10.1172/jci.insight.164296. JCI Insight. 2023. PMID: 36809274 Free PMC article.
Hyperglucagonaemia in diabetes: altered amino acid metabolism triggers mTORC1 activation, which drives glucagon production.
Riahi Y, Kogot-Levin A, Kadosh L, Agranovich B, Malka A, Assa M, Piran R, Avrahami D, Glaser B, Gottlieb E, Jackson F 3rd, Cerasi E, Bernal-Mizrachi E, Helman A, Leibowitz G. Riahi Y, et al. Among authors: agranovich b. Diabetologia. 2023 Oct;66(10):1925-1942. doi: 10.1007/s00125-023-05967-8. Epub 2023 Jul 22. Diabetologia. 2023. PMID: 37480416
Impairment of serine transport across the blood-brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction.
Radzishevsky I, Odeh M, Bodner O, Zubedat S, Shaulov L, Litvak M, Esaki K, Yoshikawa T, Agranovich B, Li WH, Radzishevsky A, Gottlieb E, Avital A, Wolosker H. Radzishevsky I, et al. Among authors: agranovich b. Proc Natl Acad Sci U S A. 2023 Oct 17;120(42):e2302780120. doi: 10.1073/pnas.2302780120. Epub 2023 Oct 9. Proc Natl Acad Sci U S A. 2023. PMID: 37812701 Free PMC article.
Kidney Proximal Tubule GLUT2-More than Meets the Eye.
Ahmad M, Abramovich I, Agranovich B, Nemirovski A, Gottlieb E, Hinden L, Tam J. Ahmad M, et al. Among authors: agranovich b. Cells. 2022 Dec 26;12(1):94. doi: 10.3390/cells12010094. Cells. 2022. PMID: 36611887 Free PMC article. Review.
Update on metabolomic findings in COPD patients.
Gea J, Enríquez-Rodríguez CJ, Agranovich B, Pascual-Guardia S. Gea J, et al. Among authors: agranovich b. ERJ Open Res. 2023 Oct 30;9(5):00180-2023. doi: 10.1183/23120541.00180-2023. eCollection 2023 Sep. ERJ Open Res. 2023. PMID: 37908399 Free PMC article. Review.
Fatty liver-mediated glycine restriction impairs glutathione synthesis and causes hypersensitization to acetaminophen.
Ghrayeb A, Agranovich B, Peled D, Finney AC, Abramovich I, Garcia JF, Traylor J, Drucker S, Fernandes SI, Weissman N, Chen YE, Rom O, Mor I, Gottlieb E. Ghrayeb A, et al. Among authors: agranovich b. bioRxiv [Preprint]. 2023 Jan 18:2023.01.16.524043. doi: 10.1101/2023.01.16.524043. bioRxiv. 2023. PMID: 36711913 Free PMC article. Preprint.
12 results