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Page 1
Inducing and exploiting vulnerabilities for the treatment of liver cancer.
Wang C, Vegna S, Jin H, Benedict B, Lieftink C, Ramirez C, de Oliveira RL, Morris B, Gadiot J, Wang W, du Chatinier A, Wang L, Gao D, Evers B, Jin G, Xue Z, Schepers A, Jochems F, Sanchez AM, Mainardi S, Te Riele H, Beijersbergen RL, Qin W, Akkari L, Bernards R. Wang C, et al. Among authors: benedict b. Nature. 2019 Oct;574(7777):268-272. doi: 10.1038/s41586-019-1607-3. Epub 2019 Oct 2. Nature. 2019. PMID: 31578521 Free PMC article.
Novel vertebrate- and brain-specific driver of neuronal outgrowth.
Jansen EJR, van Bakel NHM, Benedict B, Olde Loohuis NFM, Hafmans TGM, Chim SM, Xu J, Kolk SM, Martens GJM. Jansen EJR, et al. Among authors: benedict b. Prog Neurobiol. 2021 Jul;202:102069. doi: 10.1016/j.pneurobio.2021.102069. Epub 2021 Apr 29. Prog Neurobiol. 2021. PMID: 33933532 Free article.
SCAI promotes error-free repair of DNA interstrand crosslinks via the Fanconi anemia pathway.
Schubert L, Hendriks IA, Hertz EPT, Wu W, Sellés-Baiget S, Hoffmann S, Viswalingam KS, Gallina I, Pentakota S, Benedict B, Johansen J, Apelt K, Luijsterburg MS, Rasmussen S, Lisby M, Liu Y, Nielsen ML, Mailand N, Duxin JP. Schubert L, et al. Among authors: benedict b. EMBO Rep. 2022 Apr 5;23(4):e53639. doi: 10.15252/embr.202153639. Epub 2022 Feb 14. EMBO Rep. 2022. PMID: 35156773 Free PMC article.
The RECQL helicase prevents replication fork collapse during replication stress.
Benedict B, van Bueren MA, van Gemert FP, Lieftink C, Guerrero Llobet S, van Vugt MA, Beijersbergen RL, Te Riele H. Benedict B, et al. Life Sci Alliance. 2020 Aug 20;3(10):e202000668. doi: 10.26508/lsa.202000668. Print 2020 Oct. Life Sci Alliance. 2020. PMID: 32820027 Free PMC article.
VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates.
Mirsanaye AS, Hoffmann S, Weisser M, Mund A, Lopez Mendez B, Typas D, van den Boom J, Benedict B, Hendriks IA, Nielsen ML, Meyer H, Duxin JP, Montoya G, Mailand N. Mirsanaye AS, et al. Among authors: benedict b. Nat Commun. 2024 Mar 19;15(1):2459. doi: 10.1038/s41467-024-46760-4. Nat Commun. 2024. PMID: 38503733 Free PMC article.