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1992 2
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2020 8
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2024 4

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Page 1
CDK11 regulates pre-mRNA splicing by phosphorylation of SF3B1.
Hluchý M, Gajdušková P, Ruiz de Los Mozos I, Rájecký M, Kluge M, Berger BT, Slabá Z, Potěšil D, Weiß E, Ule J, Zdráhal Z, Knapp S, Paruch K, Friedel CC, Blazek D. Hluchý M, et al. Among authors: berger bt. Nature. 2022 Sep;609(7928):829-834. doi: 10.1038/s41586-022-05204-z. Epub 2022 Sep 14. Nature. 2022. PMID: 36104565
Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors.
Reinecke M, Brear P, Vornholz L, Berger BT, Seefried F, Wilhelm S, Samaras P, Gyenis L, Litchfield DW, Médard G, Müller S, Ruland J, Hyvönen M, Wilhelm M, Kuster B. Reinecke M, et al. Among authors: berger bt. Nat Chem Biol. 2023 Oct 30. doi: 10.1038/s41589-023-01459-3. Online ahead of print. Nat Chem Biol. 2023. PMID: 37904048
Discovery of Potent and Exquisitely Selective Inhibitors of Kinase CK1 with Tunable Isoform Selectivity.
Němec V, Khirsariya P, Janovská P, Moyano PM, Maier L, Procházková P, Kebková P, Gybel' T, Berger BT, Chaikuad A, Reinecke M, Kuster B, Knapp S, Bryja V, Paruch K. Němec V, et al. Among authors: berger bt. Angew Chem Int Ed Engl. 2023 Mar 6;62(11):e202217532. doi: 10.1002/anie.202217532. Epub 2023 Feb 2. Angew Chem Int Ed Engl. 2023. PMID: 36625768
Quantifying Target Occupancy of Small Molecules Within Living Cells.
Robers MB, Friedman-Ohana R, Huber KVM, Kilpatrick L, Vasta JD, Berger BT, Chaudhry C, Hill S, Müller S, Knapp S, Wood KV. Robers MB, et al. Among authors: berger bt. Annu Rev Biochem. 2020 Jun 20;89:557-581. doi: 10.1146/annurev-biochem-011420-092302. Epub 2020 Mar 24. Annu Rev Biochem. 2020. PMID: 32208767 Review.
Conformational plasticity of the ULK3 kinase domain.
Mathea S, Salah E, Tallant C, Chatterjee D, Berger BT, Konietzny R, Müller S, Kessler BM, Knapp S. Mathea S, et al. Among authors: berger bt. Biochem J. 2021 Jul 30;478(14):2811-2823. doi: 10.1042/BCJ20210257. Biochem J. 2021. PMID: 34190988
Structure-Based Design of Selective Salt-Inducible Kinase Inhibitors.
Tesch R, Rak M, Raab M, Berger LM, Kronenberger T, Joerger AC, Berger BT, Abdi I, Hanke T, Poso A, Strebhardt K, Sanhaji M, Knapp S. Tesch R, et al. Among authors: berger bt. J Med Chem. 2021 Jun 24;64(12):8142-8160. doi: 10.1021/acs.jmedchem.0c02144. Epub 2021 Jun 4. J Med Chem. 2021. PMID: 34086472
Resistance to kinase inhibition through shortened target engagement.
Rangwala AM, Berger BT, Robers MB, Knapp S, Seeliger MA. Rangwala AM, et al. Among authors: berger bt. Mol Cell Oncol. 2022 Jan 22;9(1):2029999. doi: 10.1080/23723556.2022.2029999. eCollection 2022. Mol Cell Oncol. 2022. PMID: 35252553 Free PMC article.
Binding Kinetics Survey of the Drugged Kinome.
Georgi V, Schiele F, Berger BT, Steffen A, Marin Zapata PA, Briem H, Menz S, Preusse C, Vasta JD, Robers MB, Brands M, Knapp S, Fernández-Montalván A. Georgi V, et al. Among authors: berger bt. J Am Chem Soc. 2018 Nov 21;140(46):15774-15782. doi: 10.1021/jacs.8b08048. Epub 2018 Nov 6. J Am Chem Soc. 2018. PMID: 30362749
Controlling the Covalent Reactivity of a Kinase Inhibitor with Light.
Reynders M, Chaikuad A, Berger BT, Bauer K, Koch P, Laufer S, Knapp S, Trauner D. Reynders M, et al. Among authors: berger bt. Angew Chem Int Ed Engl. 2021 Sep 6;60(37):20178-20183. doi: 10.1002/anie.202103767. Epub 2021 Aug 11. Angew Chem Int Ed Engl. 2021. PMID: 34081840 Free PMC article.
47 results