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Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes.
de Taeye SW, Ozorowski G, Torrents de la Peña A, Guttman M, Julien JP, van den Kerkhof TL, Burger JA, Pritchard LK, Pugach P, Yasmeen A, Crampton J, Hu J, Bontjer I, Torres JL, Arendt H, DeStefano J, Koff WC, Schuitemaker H, Eggink D, Berkhout B, Dean H, LaBranche C, Crotty S, Crispin M, Montefiori DC, Klasse PJ, Lee KK, Moore JP, Wilson IA, Ward AB, Sanders RW. de Taeye SW, et al. Among authors: berkhout b. Cell. 2015 Dec 17;163(7):1702-15. doi: 10.1016/j.cell.2015.11.056. Cell. 2015. PMID: 26687358 Free PMC article.
Evolution of live-attenuated virus vaccines.
Berkhout B, Verhoef K. Berkhout B, et al. Dev Biol (Basel). 2001;106:217-21; discussion 253-63. Dev Biol (Basel). 2001. PMID: 11761234 No abstract available.
Gene therapy as a vaccine for HIV-1.
Berkhout B, Sanders RW. Berkhout B, et al. Expert Opin Biol Ther. 2012 Oct;12(10):1315-21. doi: 10.1517/14712598.2012.707177. Epub 2012 Jul 18. Expert Opin Biol Ther. 2012. PMID: 22803517 Review.
HIV-1-based lentiviral vectors.
Liu YP, Berkhout B. Liu YP, et al. Among authors: berkhout b. Methods Mol Biol. 2014;1087:273-84. doi: 10.1007/978-1-62703-670-2_22. Methods Mol Biol. 2014. PMID: 24158830
Stabilized HIV-1 envelope glycoprotein trimers lacking the V1V2 domain, obtained by virus evolution.
Bontjer I, Melchers M, Eggink D, David K, Moore JP, Berkhout B, Sanders RW. Bontjer I, et al. Among authors: berkhout b. J Biol Chem. 2010 Nov 19;285(47):36456-70. doi: 10.1074/jbc.M110.156588. Epub 2010 Sep 8. J Biol Chem. 2010. PMID: 20826824 Free PMC article.
., Tuin, K., Baldwin, C., Pollakis, G., Paxton, W. A., Braakman, I., Berkhout, B., and Sanders, R. W. (2009) J. Virol. 83, 368-383). We now show that specific compensatory changes improved the function of deltaV1V2 Env proteins and hence HIV-1 replication. ...
., Tuin, K., Baldwin, C., Pollakis, G., Paxton, W. A., Braakman, I., Berkhout, B., and Sanders, R. W. (2009) J. Virol. 83, 368 …
599 results