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Mitotane therapy in adrenocortical cancer induces CYP3A4 and inhibits 5α-reductase, explaining the need for personalized glucocorticoid and androgen replacement.
Chortis V, Taylor AE, Schneider P, Tomlinson JW, Hughes BA, O'Neil DM, Libé R, Allolio B, Bertagna X, Bertherat J, Beuschlein F, Fassnacht M, Karavitaki N, Mannelli M, Mantero F, Opocher G, Porfiri E, Quinkler M, Sherlock M, Terzolo M, Nightingale P, Shackleton CH, Stewart PM, Hahner S, Arlt W. Chortis V, et al. Among authors: beuschlein f. J Clin Endocrinol Metab. 2013 Jan;98(1):161-71. doi: 10.1210/jc.2012-2851. Epub 2012 Nov 16. J Clin Endocrinol Metab. 2013. PMID: 23162091 Free article. Clinical Trial.
[Adrenal cortex insufficiency: diagnosis and therapy].
Arlt W, Beuschlein F, Allolio B. Arlt W, et al. Among authors: beuschlein f. Med Klin (Munich). 1999 Jun 15;94(6):353-4. doi: 10.1007/BF03044895. Med Klin (Munich). 1999. PMID: 10420728 German. No abstract available.
[Cushing syndrome: diagnosis and therapy].
Beuschlein F, Arlt W, Allolio B. Beuschlein F, et al. Med Klin (Munich). 1999 Jul 15;94(7):395-6. doi: 10.1007/BF03044905. Med Klin (Munich). 1999. PMID: 10437371 Review. German. No abstract available.
489 results