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TRAF6 is a nexus for TLR-STAT1 crosstalk.
Bezbradica JS, Schroder K. Bezbradica JS, et al. Immunol Cell Biol. 2014 Oct;92(9):737-8. doi: 10.1038/icb.2014.71. Epub 2014 Aug 12. Immunol Cell Biol. 2014. PMID: 25112830 No abstract available.
Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity.
Boucher D, Monteleone M, Coll RC, Chen KW, Ross CM, Teo JL, Gomez GA, Holley CL, Bierschenk D, Stacey KJ, Yap AS, Bezbradica JS, Schroder K. Boucher D, et al. Among authors: bezbradica js. J Exp Med. 2018 Mar 5;215(3):827-840. doi: 10.1084/jem.20172222. Epub 2018 Feb 6. J Exp Med. 2018. PMID: 29432122 Free PMC article.
Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion.
Monteleone M, Stanley AC, Chen KW, Brown DL, Bezbradica JS, von Pein JB, Holley CL, Boucher D, Shakespear MR, Kapetanovic R, Rolfes V, Sweet MJ, Stow JL, Schroder K. Monteleone M, et al. Among authors: bezbradica js. Cell Rep. 2018 Aug 7;24(6):1425-1433. doi: 10.1016/j.celrep.2018.07.027. Cell Rep. 2018. PMID: 30089254 Free article.
TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation.
Fischer FA, Mies LFM, Nizami S, Pantazi E, Danielli S, Demarco B, Ohlmeyer M, Lee MSJ, Coban C, Kagan JC, Di Daniel E, Bezbradica JS. Fischer FA, et al. Among authors: bezbradica js. Proc Natl Acad Sci U S A. 2021 Sep 21;118(38):e2009309118. doi: 10.1073/pnas.2009309118. Proc Natl Acad Sci U S A. 2021. PMID: 34518217 Free PMC article.
46 results