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Electrophysiological Abnormalities in VLCAD Deficient hiPSC-Cardiomyocytes Can Be Improved by Lowering Accumulation of Fatty Acid Oxidation Intermediates.
Knottnerus SJG, Mengarelli I, Wüst RCI, Baartscheer A, Bleeker JC, Coronel R, Ferdinandusse S, Guan K, IJlst L, Li W, Luo X, Portero VM, Ulbricht Y, Visser G, Wanders RJA, Wijburg FA, Verkerk AO, Houtkooper RH, Bezzina CR. Knottnerus SJG, et al. Among authors: bezzina cr. Int J Mol Sci. 2020 Apr 8;21(7):2589. doi: 10.3390/ijms21072589. Int J Mol Sci. 2020. PMID: 32276429 Free PMC article.
Genetic control of sodium channel function.
Tan HL, Bezzina CR, Smits JP, Verkerk AO, Wilde AA. Tan HL, et al. Among authors: bezzina cr. Cardiovasc Res. 2003 Mar 15;57(4):961-73. doi: 10.1016/s0008-6363(02)00714-9. Cardiovasc Res. 2003. PMID: 12650874 Review.
A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization.
Bezzina CR, Verkerk AO, Busjahn A, Jeron A, Erdmann J, Koopmann TT, Bhuiyan ZA, Wilders R, Mannens MM, Tan HL, Luft FC, Schunkert H, Wilde AA. Bezzina CR, et al. Cardiovasc Res. 2003 Jul 1;59(1):27-36. doi: 10.1016/s0008-6363(03)00342-0. Cardiovasc Res. 2003. PMID: 12829173
Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada syndrome: a combined electrophysiological, genetic, histopathologic, and computational study.
Coronel R, Casini S, Koopmann TT, Wilms-Schopman FJ, Verkerk AO, de Groot JR, Bhuiyan Z, Bezzina CR, Veldkamp MW, Linnenbank AC, van der Wal AC, Tan HL, Brugada P, Wilde AA, de Bakker JM. Coronel R, et al. Among authors: bezzina cr. Circulation. 2005 Nov 1;112(18):2769-77. doi: 10.1161/CIRCULATIONAHA.105.532614. Circulation. 2005. PMID: 16267250
Overlap syndrome of cardiac sodium channel disease in mice carrying the equivalent mutation of human SCN5A-1795insD.
Remme CA, Verkerk AO, Nuyens D, van Ginneken AC, van Brunschot S, Belterman CN, Wilders R, van Roon MA, Tan HL, Wilde AA, Carmeliet P, de Bakker JM, Veldkamp MW, Bezzina CR. Remme CA, et al. Among authors: bezzina cr. Circulation. 2006 Dec 12;114(24):2584-94. doi: 10.1161/CIRCULATIONAHA.106.653949. Epub 2006 Dec 4. Circulation. 2006. PMID: 17145985
Genetically determined differences in sodium current characteristics modulate conduction disease severity in mice with cardiac sodium channelopathy.
Remme CA, Scicluna BP, Verkerk AO, Amin AS, van Brunschot S, Beekman L, Deneer VH, Chevalier C, Oyama F, Miyazaki H, Nukina N, Wilders R, Escande D, Houlgatte R, Wilde AA, Tan HL, Veldkamp MW, de Bakker JM, Bezzina CR. Remme CA, et al. Among authors: bezzina cr. Circ Res. 2009 Jun 5;104(11):1283-92. doi: 10.1161/CIRCRESAHA.109.194423. Epub 2009 Apr 30. Circ Res. 2009. PMID: 19407241
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