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mRNA therapeutics: beyond vaccine applications.
Bhat B, Karve S, Anderson DG. Bhat B, et al. Trends Mol Med. 2021 Sep;27(9):923-924. doi: 10.1016/j.molmed.2021.05.004. Epub 2021 Jun 23. Trends Mol Med. 2021. PMID: 34172390 Free article. No abstract available.
Gene activation of SMN by selective disruption of lncRNA-mediated recruitment of PRC2 for the treatment of spinal muscular atrophy.
Woo CJ, Maier VK, Davey R, Brennan J, Li G, Brothers J 2nd, Schwartz B, Gordo S, Kasper A, Okamoto TR, Johansson HE, Mandefro B, Sareen D, Bialek P, Chau BN, Bhat B, Bullough D, Barsoum J. Woo CJ, et al. Among authors: bhat b. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1509-E1518. doi: 10.1073/pnas.1616521114. Epub 2017 Feb 13. Proc Natl Acad Sci U S A. 2017. PMID: 28193854 Free PMC article.
Competition for RISC binding predicts in vitro potency of siRNA.
Koller E, Propp S, Murray H, Lima W, Bhat B, Prakash TP, Allerson CR, Swayze EE, Marcusson EG, Dean NM. Koller E, et al. Among authors: bhat b. Nucleic Acids Res. 2006;34(16):4467-76. doi: 10.1093/nar/gkl589. Epub 2006 Aug 31. Nucleic Acids Res. 2006. PMID: 16945958 Free PMC article.
Potent inhibition of microRNA in vivo without degradation.
Davis S, Propp S, Freier SM, Jones LE, Serra MJ, Kinberger G, Bhat B, Swayze EE, Bennett CF, Esau C. Davis S, et al. Among authors: bhat b. Nucleic Acids Res. 2009 Jan;37(1):70-7. doi: 10.1093/nar/gkn904. Epub 2008 Nov 16. Nucleic Acids Res. 2009. PMID: 19015151 Free PMC article.
542 results