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Pathogenesis of Respiratory Viral and Fungal Coinfections.
Salazar F, Bignell E, Brown GD, Cook PC, Warris A. Salazar F, et al. Among authors: bignell e. Clin Microbiol Rev. 2022 Jan 19;35(1):e0009421. doi: 10.1128/CMR.00094-21. Epub 2021 Nov 17. Clin Microbiol Rev. 2022. PMID: 34788127 Free PMC article. Review.
Tackling the emerging threat of antifungal resistance to human health.
Fisher MC, Alastruey-Izquierdo A, Berman J, Bicanic T, Bignell EM, Bowyer P, Bromley M, Brüggemann R, Garber G, Cornely OA, Gurr SJ, Harrison TS, Kuijper E, Rhodes J, Sheppard DC, Warris A, White PL, Xu J, Zwaan B, Verweij PE. Fisher MC, et al. Among authors: bignell em. Nat Rev Microbiol. 2022 Sep;20(9):557-571. doi: 10.1038/s41579-022-00720-1. Epub 2022 Mar 29. Nat Rev Microbiol. 2022. PMID: 35352028 Free PMC article. Review.
Conserved and Divergent Features of pH Sensing in Major Fungal Pathogens.
Farhadi Cheshmeh Morvari S, McCann BL, Bignell EM. Farhadi Cheshmeh Morvari S, et al. Among authors: bignell em. Curr Clin Microbiol Rep. 2023;10(3):120-130. doi: 10.1007/s40588-023-00195-5. Epub 2023 Jul 28. Curr Clin Microbiol Rep. 2023. PMID: 37577059 Free PMC article. Review.
The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus.
Furukawa T, van Rhijn N, Fraczek M, Gsaller F, Davies E, Carr P, Gago S, Fortune-Grant R, Rahman S, Gilsenan JM, Houlder E, Kowalski CH, Raj S, Paul S, Cook P, Parker JE, Kelly S, Cramer RA, Latgé JP, Moye-Rowley S, Bignell E, Bowyer P, Bromley MJ. Furukawa T, et al. Among authors: bignell e. Nat Commun. 2020 Jan 22;11(1):427. doi: 10.1038/s41467-019-14191-1. Nat Commun. 2020. PMID: 31969561 Free PMC article.
Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response.
Sueiro-Olivares M, Scott J, Gago S, Petrovic D, Kouroussis E, Zivanovic J, Yu Y, Strobel M, Cunha C, Thomson D, Fortune-Grant R, Thusek S, Bowyer P, Beilhack A, Carvalho A, Bignell E, Filipovic MR, Amich J. Sueiro-Olivares M, et al. Among authors: bignell e. PLoS Biol. 2021 Jun 1;19(6):e3001247. doi: 10.1371/journal.pbio.3001247. eCollection 2021 Jun. PLoS Biol. 2021. PMID: 34061822 Free PMC article.
Distinct Cohorts of Aspergillus fumigatus Transcription Factors Are Required for Epithelial Damage Occurring via Contact- or Soluble Effector-Mediated Mechanisms.
Rahman S, van Rhijn N, Papastamoulis P, Thomson DD, Carter Z, Fortune-Grant R, Rattray M, Bromley MJ, Bignell E. Rahman S, et al. Among authors: bignell e. Front Cell Infect Microbiol. 2022 Jul 28;12:907519. doi: 10.3389/fcimb.2022.907519. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35982778 Free PMC article.
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