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Epigenetic modification of the FMR1 gene in fragile X syndrome is associated with differential response to the mGluR5 antagonist AFQ056.
Jacquemont S, Curie A, des Portes V, Torrioli MG, Berry-Kravis E, Hagerman RJ, Ramos FJ, Cornish K, He Y, Paulding C, Neri G, Chen F, Hadjikhani N, Martinet D, Meyer J, Beckmann JS, Delange K, Brun A, Bussy G, Gasparini F, Hilse T, Floesser A, Branson J, Bilbe G, Johns D, Gomez-Mancilla B. Jacquemont S, et al. Among authors: bilbe g. Sci Transl Med. 2011 Jan 5;3(64):64ra1. doi: 10.1126/scitranslmed.3001708. Sci Transl Med. 2011. PMID: 21209411 Clinical Trial.
Metabotropic glutamate receptor type 5 in levodopa-induced motor complications.
Ouattara B, Grégoire L, Morissette M, Gasparini F, Vranesic I, Bilbe G, Johns DR, Rajput A, Hornykiewicz O, Rajput AH, Gomez-Mancilla B, Di Paolo T. Ouattara B, et al. Among authors: bilbe g. Neurobiol Aging. 2011 Jul;32(7):1286-95. doi: 10.1016/j.neurobiolaging.2009.07.014. Epub 2009 Dec 29. Neurobiol Aging. 2011. PMID: 20036444
The acute antiparkinsonian and antidyskinetic effect of AFQ056, a novel metabotropic glutamate receptor type 5 antagonist, in L-Dopa-treated parkinsonian monkeys.
Grégoire L, Morin N, Ouattara B, Gasparini F, Bilbe G, Johns D, Vranesic I, Sahasranaman S, Gomez-Mancilla B, Di Paolo T. Grégoire L, et al. Among authors: bilbe g. Parkinsonism Relat Disord. 2011 May;17(4):270-6. doi: 10.1016/j.parkreldis.2011.01.008. Epub 2011 Feb 15. Parkinsonism Relat Disord. 2011. PMID: 21315648
Neuropathology in mice expressing human alpha-synuclein.
van der Putten H, Wiederhold KH, Probst A, Barbieri S, Mistl C, Danner S, Kauffmann S, Hofele K, Spooren WP, Ruegg MA, Lin S, Caroni P, Sommer B, Tolnay M, Bilbe G. van der Putten H, et al. Among authors: bilbe g. J Neurosci. 2000 Aug 15;20(16):6021-9. doi: 10.1523/JNEUROSCI.20-16-06021.2000. J Neurosci. 2000. PMID: 10934251 Free PMC article.
Mouse models of alpha-synucleinopathy and Lewy pathology.
Sommer B, Barbieri S, Hofele K, Wiederhold K, Probst A, Mistl C, Danner S, Kauffmann S, Spooren W, Tolnay M, Bilbe G, van der Putten H, Kafmann S, Caromi P, Ruegg MA. Sommer B, et al. Among authors: bilbe g. Exp Gerontol. 2000 Dec;35(9-10):1389-403. doi: 10.1016/s0531-5565(00)00181-9. Exp Gerontol. 2000. PMID: 11113617
Global down-regulation of gene expression in the brain using RNA interference, with emphasis on monoamine transporters and GPCRs: implications for target characterization in psychiatric and neurological disorders.
Hoyer D, Thakker DR, Natt F, Maier R, Huesken D, Müller M, Flor P, VAN DER Putten H, Schmutz M, Bilbe G, Cryan JF. Hoyer D, et al. Among authors: bilbe g. J Recept Signal Transduct Res. 2006;26(5-6):527-47. doi: 10.1080/10799890600929663. J Recept Signal Transduct Res. 2006. PMID: 17118797
84 results