Binder GK - Search Results

1

Efficient lentiviral vector-mediated control of HIV-1 replication in CD4 lymphocytes from diverse HIV+ infected patients grouped according to CD4 count and viral load.

Humeau LM, Binder GK, Lu X, Slepushkin V, Merling R, Echeagaray P, Pereira M, Slepushkina T, Barnett S, Dropulic LK, Carroll R, Levine BL, June CH, Dropulic B. Humeau LM, et al. Among authors: binder gk. Mol Ther. 2004 Jun;9(6):902-13. doi: 10.1016/j.ymthe.2004.03.005. Mol Ther. 2004. PMID: 15194057 Free article.

2

Antisense-mediated inhibition of human immunodeficiency virus (HIV) replication by use of an HIV type 1-based vector results in severely attenuated mutants incapable of developing resistance.

Lu X, Yu Q, Binder GK, Chen Z, Slepushkina T, Rossi J, Dropulic B. Lu X, et al. Among authors: binder gk. J Virol. 2004 Jul;78(13):7079-88. doi: 10.1128/JVI.78.13.7079-7088.2004. J Virol. 2004. PMID: 15194784 Free PMC article.

3

Regulatory considerations for novel gene therapy products: a review of the process leading to the first clinical lentiviral vector.

Manilla P, Rebello T, Afable C, Lu X, Slepushkin V, Humeau LM, Schonely K, Ni Y, Binder GK, Levine BL, MacGregor RR, June CH, Dropulic B. Manilla P, et al. Among authors: binder gk. Hum Gene Ther. 2005 Jan;16(1):17-25. doi: 10.1089/hum.2005.16.17. Hum Gene Ther. 2005. PMID: 15703485 Review.

4

Inhibition of simian/human immunodeficiency virus replication in CD4+ T cells derived from lentiviral-transduced CD34+ hematopoietic cells.

Braun SE, Wong FE, Connole M, Qiu G, Lee L, Gillis J, Lu X, Humeau L, Slepushkin V, Binder GK, Dropulic B, Johnson RP. Braun SE, et al. Among authors: binder gk. Mol Ther. 2005 Dec;12(6):1157-67. doi: 10.1016/j.ymthe.2005.07.698. Epub 2005 Sep 15. Mol Ther. 2005. PMID: 16168713 Free article.

5

Analysis of lentiviral vector integration in HIV+ study subjects receiving autologous infusions of gene modified CD4+ T cells.

Wang GP, Levine BL, Binder GK, Berry CC, Malani N, McGarrity G, Tebas P, June CH, Bushman FD. Wang GP, et al. Among authors: binder gk. Mol Ther. 2009 May;17(5):844-50. doi: 10.1038/mt.2009.16. Epub 2009 Mar 3. Mol Ther. 2009. PMID: 19259065 Free PMC article.

6

Safe two-plasmid production for the first clinical lentivirus vector that achieves >99% transduction in primary cells using a one-step protocol.

Lu X, Humeau L, Slepushkin V, Binder G, Yu Q, Slepushkina T, Chen Z, Merling R, Davis B, Chang YN, Dropulic B. Lu X, et al. J Gene Med. 2004 Sep;6(9):963-73. doi: 10.1002/jgm.593. J Gene Med. 2004. PMID: 15352069

7

Generation of a packaging cell line for prolonged large-scale production of high-titer HIV-1-based lentiviral vector.

Ni Y, Sun S, Oparaocha I, Humeau L, Davis B, Cohen R, Binder G, Chang YN, Slepushkin V, Dropulic B. Ni Y, et al. J Gene Med. 2005 Jun;7(6):818-34. doi: 10.1002/jgm.726. J Gene Med. 2005. PMID: 15693055

8

Gene transfer in humans using a conditionally replicating lentiviral vector.

Levine BL, Humeau LM, Boyer J, MacGregor RR, Rebello T, Lu X, Binder GK, Slepushkin V, Lemiale F, Mascola JR, Bushman FD, Dropulic B, June CH. Levine BL, et al. Among authors: binder gk. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17372-7. doi: 10.1073/pnas.0608138103. Epub 2006 Nov 7. Proc Natl Acad Sci U S A. 2006. PMID: 17090675 Free PMC article.

9

ABC transporter inhibitors that are substrates enhance lentiviral vector transduction into primitive hematopoietic progenitor cells.

Davis BM, Humeau L, Slepushkin V, Binder G, Korshalla L, Ni Y, Ogunjimi EO, Chang LF, Lu X, Dropulic B. Davis BM, et al. Blood. 2004 Jul 15;104(2):364-73. doi: 10.1182/blood-2003-07-2363. Epub 2004 Apr 1. Blood. 2004. PMID: 15059841 Free article.

10

Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo.

Milone MC, Fish JD, Carpenito C, Carroll RG, Binder GK, Teachey D, Samanta M, Lakhal M, Gloss B, Danet-Desnoyers G, Campana D, Riley JL, Grupp SA, June CH. Milone MC, et al. Among authors: binder gk. Mol Ther. 2009 Aug;17(8):1453-64. doi: 10.1038/mt.2009.83. Epub 2009 Apr 21. Mol Ther. 2009. PMID: 19384291 Free PMC article.

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