Bingham JP - Search Results

1

Increased sensitivity to platinum drugs of cancer cells with acquired resistance to trabectedin.

Colmegna B, Uboldi S, Frapolli R, Licandro SA, Panini N, Galmarini CM, Badri N, Spanswick VJ, Bingham JP, Kiakos K, Erba E, Hartley JA, D'Incalci M. Colmegna B, et al. Among authors: bingham jp. Br J Cancer. 2015 Dec 22;113(12):1687-93. doi: 10.1038/bjc.2015.407. Epub 2015 Dec 3. Br J Cancer. 2015. PMID: 26633559 Free PMC article.

2

Evidence for different mechanisms of 'unhooking' for melphalan and cisplatin-induced DNA interstrand cross-links in vitro and in clinical acquired resistant tumour samples.

Spanswick VJ, Lowe HL, Newton C, Bingham JP, Bagnobianchi A, Kiakos K, Craddock C, Ledermann JA, Hochhauser D, Hartley JA. Spanswick VJ, et al. Among authors: bingham jp. BMC Cancer. 2012 Sep 28;12:436. doi: 10.1186/1471-2407-12-436. BMC Cancer. 2012. PMID: 23020514 Free PMC article.

3

DNA damage by anticancer agents and its repair: mapping in cells at the subgene level with quantitative polymerase chain reaction.

Grimaldi KA, Bingham JP, Souhami RL, Hartley JA. Grimaldi KA, et al. Among authors: bingham jp. Anal Biochem. 1994 Oct;222(1):236-42. doi: 10.1006/abio.1994.1479. Anal Biochem. 1994. PMID: 7856855

4

Strand-specific measurement of cisplatin-induced DNA damage and repair using quantitative PCR.

Bingham JP, Hartley JA, Souhami RL, Grimaldi KA. Bingham JP, et al. Nucleic Acids Res. 1996 Mar 1;24(5):987-9. doi: 10.1093/nar/24.5.987. Nucleic Acids Res. 1996. PMID: 8600473 Free PMC article. No abstract available.

5

PCR-based assays for strand-specific measurement of DNA damage and repair. I. Strand-specific quantitative PCR.

Grimaldi KA, Bingham JP, Hartley JA. Grimaldi KA, et al. Among authors: bingham jp. Methods Mol Biol. 1999;113:227-40. doi: 10.1385/1-59259-675-4:227. Methods Mol Biol. 1999. PMID: 10443424 No abstract available.

6

DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards is preserved in intact cells.

Hartley JA, Bingham JP, Souhami RL. Hartley JA, et al. Among authors: bingham jp. Nucleic Acids Res. 1992 Jun 25;20(12):3175-8. doi: 10.1093/nar/20.12.3175. Nucleic Acids Res. 1992. PMID: 1620613 Free PMC article.

7

Pre-clinical pharmacology and mechanism of action of SG3199, the pyrrolobenzodiazepine (PBD) dimer warhead component of antibody-drug conjugate (ADC) payload tesirine.

Hartley JA, Flynn MJ, Bingham JP, Corbett S, Reinert H, Tiberghien A, Masterson LA, Antonow D, Adams L, Chowdhury S, Williams DG, Mao S, Harper J, Havenith CEG, Zammarchi F, Chivers S, van Berkel PH, Howard PW. Hartley JA, et al. Among authors: bingham jp. Sci Rep. 2018 Jul 11;8(1):10479. doi: 10.1038/s41598-018-28533-4. Sci Rep. 2018. PMID: 29992976 Free PMC article.

8

Minor structural modifications to alchemix influence mechanism of action and pharmacological activity.

Abdallah QM, Phillips RM, Johansson F, Helleday T, Cosentino L, Abdel-Rahman H, Etzad J, Wheelhouse RT, Kiakos K, Bingham JP, Hartley JA, Patterson LH, Pors K. Abdallah QM, et al. Among authors: bingham jp. Biochem Pharmacol. 2012 Jun 1;83(11):1514-22. doi: 10.1016/j.bcp.2012.02.017. Epub 2012 Mar 1. Biochem Pharmacol. 2012. PMID: 22387433 Free article.

9

Targeting of tumor cells and DNA by a chlorambucil-spermidine conjugate.

Holley JL, Mather A, Wheelhouse RT, Cullis PM, Hartley JA, Bingham JP, Cohen GM. Holley JL, et al. Among authors: bingham jp. Cancer Res. 1992 Aug 1;52(15):4190-5. Cancer Res. 1992. PMID: 1638533

10

AzaHx, a novel fluorescent, DNA minor groove and G·C recognition element: Synthesis and DNA binding properties of a p-anisyl-4-aza-benzimidazole-pyrrole-imidazole (azaHx-PI) polyamide.

Satam V, Babu B, Patil P, Brien KA, Olson K, Savagian M, Lee M, Mepham A, Jobe LB, Bingham JP, Pett L, Wang S, Ferrara M, Bruce CD, Wilson WD, Lee M, Hartley JA, Kiakos K. Satam V, et al. Among authors: bingham jp. Bioorg Med Chem Lett. 2015 Sep 1;25(17):3681-5. doi: 10.1016/j.bmcl.2015.06.055. Epub 2015 Jun 19. Bioorg Med Chem Lett. 2015. PMID: 26122210

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