Blower PE - Search Results

1

Pharmacogenomics approach reveals MRP1 (ABCC1)-mediated resistance to geldanamycins.

Pham AN, Wang J, Fang J, Gao X, Zhang Y, Blower PE, Sadée W, Huang Y. Pham AN, et al. Among authors: blower pe. Pharm Res. 2009 Apr;26(4):936-45. doi: 10.1007/s11095-008-9796-8. Epub 2008 Dec 10. Pharm Res. 2009. PMID: 19067123

2

Pharmacogenomic approach reveals a role for the x(c)- cystine/glutamate antiporter in growth and celastrol resistance of glioma cell lines.

Pham AN, Blower PE, Alvarado O, Ravula R, Gout PW, Huang Y. Pham AN, et al. Among authors: blower pe. J Pharmacol Exp Ther. 2010 Mar;332(3):949-58. doi: 10.1124/jpet.109.162248. Epub 2009 Dec 9. J Pharmacol Exp Ther. 2010. PMID: 20007406

3

Chemogenomic analysis identifies geldanamycins as substrates and inhibitors of ABCB1.

Huang Y, Blower PE, Liu R, Dai Z, Pham AN, Moon H, Fang J, Sadée W. Huang Y, et al. Among authors: blower pe. Pharm Res. 2007 Sep;24(9):1702-12. doi: 10.1007/s11095-007-9300-x. Epub 2007 Apr 25. Pharm Res. 2007. PMID: 17457659

4

Cystine-glutamate transporter SLC7A11 mediates resistance to geldanamycin but not to 17-(allylamino)-17-demethoxygeldanamycin.

Liu R, Blower PE, Pham AN, Fang J, Dai Z, Wise C, Green B, Teitel CH, Ning B, Ling W, Lyn-Cook BD, Kadlubar FF, Sadée W, Huang Y. Liu R, et al. Among authors: blower pe. Mol Pharmacol. 2007 Dec;72(6):1637-46. doi: 10.1124/mol.107.039644. Epub 2007 Sep 17. Mol Pharmacol. 2007. PMID: 17875604

5

Correlating gene expression with chemical scaffolds of cytotoxic agents: ellipticines as substrates and inhibitors of MDR1.

Huang Y, Blower PE, Yang C, Barbacioru C, Dai Z, Zhang Y, Xiao JJ, Chan KK, Sadée W. Huang Y, et al. Among authors: blower pe. Pharmacogenomics J. 2005;5(2):112-25. doi: 10.1038/sj.tpj.6500297. Pharmacogenomics J. 2005. PMID: 15668728

6

Chemoinformatics analysis identifies cytotoxic compounds susceptible to chemoresistance mediated by glutathione and cystine/glutamate transport system xc-.

Dai Z, Huang Y, Sadee W, Blower P. Dai Z, et al. J Med Chem. 2007 Apr 19;50(8):1896-906. doi: 10.1021/jm060960h. Epub 2007 Mar 17. J Med Chem. 2007. PMID: 17367118

7

MicroRNAs modulate the chemosensitivity of tumor cells.

Blower PE, Chung JH, Verducci JS, Lin S, Park JK, Dai Z, Liu CG, Schmittgen TD, Reinhold WC, Croce CM, Weinstein JN, Sadee W. Blower PE, et al. Mol Cancer Ther. 2008 Jan;7(1):1-9. doi: 10.1158/1535-7163.MCT-07-0573. Epub 2008 Jan 9. Mol Cancer Ther. 2008. PMID: 18187804

8

MicroRNA expression profiles for the NCI-60 cancer cell panel.

Blower PE, Verducci JS, Lin S, Zhou J, Chung JH, Dai Z, Liu CG, Reinhold W, Lorenzi PL, Kaldjian EP, Croce CM, Weinstein JN, Sadee W. Blower PE, et al. Mol Cancer Ther. 2007 May;6(5):1483-91. doi: 10.1158/1535-7163.MCT-07-0009. Epub 2007 May 4. Mol Cancer Ther. 2007. PMID: 17483436

9

Pharmacogenomic analysis: correlating molecular substructure classes with microarray gene expression data.

Blower PE, Yang C, Fligner MA, Verducci JS, Yu L, Richman S, Weinstein JN. Blower PE, et al. Pharmacogenomics J. 2002;2(4):259-71. doi: 10.1038/sj.tpj.6500116. Pharmacogenomics J. 2002. PMID: 12196914

10

In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation.

Ikediobi ON, Reimers M, Durinck S, Blower PE, Futreal AP, Stratton MR, Weinstein JN. Ikediobi ON, et al. Among authors: blower pe. Mol Cancer Ther. 2008 Jun;7(6):1337-46. doi: 10.1158/1535-7163.MCT-07-2308. Epub 2008 Jun 4. Mol Cancer Ther. 2008. PMID: 18524847 Free PMC article.

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