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Hypothesizing that brain reward circuitry genes are genetic antecedents of pain sensitivity and critical diagnostic and pharmacogenomic treatment targets for chronic pain conditions.
Chen AL, Chen TJ, Waite RL, Reinking J, Tung HL, Rhoades P, Downs BW, Braverman E, Braverman D, Kerner M, Blum SH, DiNubile N, Smith D, Oscar-Berman M, Prihoda TJ, Floyd JB, O'Brien D, Liu HH, Blum K. Chen AL, et al. Among authors: blum sh, blum k. Med Hypotheses. 2009 Jan;72(1):14-22. doi: 10.1016/j.mehy.2008.07.059. Epub 2008 Oct 31. Med Hypotheses. 2009. PMID: 18951726 Free PMC article. Review.
Activation instead of blocking mesolimbic dopaminergic reward circuitry is a preferred modality in the long term treatment of reward deficiency syndrome (RDS): a commentary.
Blum K, Chen AL, Chen TJ, Braverman ER, Reinking J, Blum SH, Cassel K, Downs BW, Waite RL, Williams L, Prihoda TJ, Kerner MM, Palomo T, Comings DE, Tung H, Rhoades P, Oscar-Berman M. Blum K, et al. Among authors: blum sh. Theor Biol Med Model. 2008 Nov 12;5:24. doi: 10.1186/1742-4682-5-24. Theor Biol Med Model. 2008. PMID: 19014506 Free PMC article. Review.
Neuro-psychopharmacogenetics and Neurological Antecedents of Posttraumatic Stress Disorder: Unlocking the Mysteries of Resilience and Vulnerability.
Bowirrat A, Chen TJ, Blum K, Madigan M, Bailey JA, Chuan Chen AL, Downs BW, Braverman ER, Radi S, Waite RL, Kerner M, Giordano J, Morse S, Oscar-Berman M, Gold M. Bowirrat A, et al. Among authors: blum k. Curr Neuropharmacol. 2010 Dec;8(4):335-58. doi: 10.2174/157015910793358123. Curr Neuropharmacol. 2010. PMID: 21629442 Free PMC article.
Can the chronic administration of the combination of buprenorphine and naloxone block dopaminergic activity causing anti-reward and relapse potential?
Blum K, Chen TJ, Bailey J, Bowirrat A, Femino J, Chen AL, Simpatico T, Morse S, Giordano J, Damle U, Kerner M, Braverman ER, Fornari F, Downs BW, Rector C, Barh D, Oscar-Berman M. Blum K, et al. Mol Neurobiol. 2011 Dec;44(3):250-68. doi: 10.1007/s12035-011-8206-0. Epub 2011 Sep 24. Mol Neurobiol. 2011. PMID: 21948099 Free PMC article.
Epigenetics in Developmental Disorder: ADHD and Endophenotypes.
Archer T, Oscar-Berman M, Blum K. Archer T, et al. Among authors: blum k. J Genet Syndr Gene Ther. 2011 Jun 30;2(104):1000104. doi: 10.4172/2157-7412.1000104. J Genet Syndr Gene Ther. 2011. PMID: 22224195 Free PMC article.
818 results