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194 results

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Page 1
Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation.
Hamarsheh S, Osswald L, Saller BS, Unger S, De Feo D, Vinnakota JM, Konantz M, Uhl FM, Becker H, Lübbert M, Shoumariyeh K, Schürch C, Andrieux G, Venhoff N, Schmitt-Graeff A, Duquesne S, Pfeifer D, Cooper MA, Lengerke C, Boerries M, Duyster J, Niemeyer CM, Erlacher M, Blazar BR, Becher B, Groß O, Brummer T, Zeiser R. Hamarsheh S, et al. Among authors: boerries m. Nat Commun. 2020 Apr 3;11(1):1659. doi: 10.1038/s41467-020-15497-1. Nat Commun. 2020. PMID: 32246016 Free PMC article.
B-Raf inhibitors induce epithelial differentiation in BRAF-mutant colorectal cancer cells.
Herr R, Köhler M, Andrlová H, Weinberg F, Möller Y, Halbach S, Lutz L, Mastroianni J, Klose M, Bittermann N, Kowar S, Zeiser R, Olayioye MA, Lassmann S, Busch H, Boerries M, Brummer T. Herr R, et al. Among authors: boerries m. Cancer Res. 2015 Jan 1;75(1):216-29. doi: 10.1158/0008-5472.CAN-13-3686. Epub 2014 Nov 7. Cancer Res. 2015. PMID: 25381152
The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer.
Krebs AM, Mitschke J, Lasierra Losada M, Schmalhofer O, Boerries M, Busch H, Boettcher M, Mougiakakos D, Reichardt W, Bronsert P, Brunton VG, Pilarsky C, Winkler TH, Brabletz S, Stemmler MP, Brabletz T. Krebs AM, et al. Among authors: boerries m. Nat Cell Biol. 2017 May;19(5):518-529. doi: 10.1038/ncb3513. Epub 2017 Apr 17. Nat Cell Biol. 2017. PMID: 28414315
Biglycan expression in the melanoma microenvironment promotes invasiveness via increased tissue stiffness inducing integrin-β1 expression.
Andrlová H, Mastroianni J, Madl J, Kern JS, Melchinger W, Dierbach H, Wernet F, Follo M, Technau-Hafsi K, Has C, Rao Mittapalli V, Idzko M, Herr R, Brummer T, Ungefroren H, Busch H, Boerries M, Narr A, Ihorst G, Vennin C, Schmitt-Graeff A, Minguet S, Timpson P, Duyster J, Meiss F, Römer W, Zeiser R. Andrlová H, et al. Among authors: boerries m. Oncotarget. 2017 Jun 27;8(26):42901-42916. doi: 10.18632/oncotarget.17160. Oncotarget. 2017. PMID: 28476030 Free PMC article.
Epithelioid hemangioendotheliomas of the liver and lung in children and adolescents.
Hettmer S, Andrieux G, Hochrein J, Kurz P, Rössler J, Lassmann S, Werner M, von Bubnoff N, Peters C, Koscielniak E, Sparber-Sauer M, Niemeyer C, Mentzel T, Busch H, Boerries M. Hettmer S, et al. Among authors: boerries m. Pediatr Blood Cancer. 2017 Dec;64(12). doi: 10.1002/pbc.26675. Epub 2017 Jun 9. Pediatr Blood Cancer. 2017. PMID: 28598585 Review.
Specific role of RhoC in tumor invasion and metastasis.
Lang S, Busch H, Boerries M, Brummer T, Timme S, Lassmann S, Aktories K, Schmidt G. Lang S, et al. Among authors: boerries m. Oncotarget. 2017 Sep 16;8(50):87364-87378. doi: 10.18632/oncotarget.20957. eCollection 2017 Oct 20. Oncotarget. 2017. PMID: 29152087 Free PMC article.
Constitutional SAMD9L mutations cause familial myelodysplastic syndrome and transient monosomy 7.
Pastor VB, Sahoo SS, Boklan J, Schwabe GC, Saribeyoglu E, Strahm B, Lebrecht D, Voss M, Bryceson YT, Erlacher M, Ehninger G, Niewisch M, Schlegelberger B, Baumann I, Achermann JC, Shimamura A, Hochrein J, Tedgård U, Nilsson L, Hasle H, Boerries M, Busch H, Niemeyer CM, Wlodarski MW. Pastor VB, et al. Among authors: boerries m. Haematologica. 2018 Mar;103(3):427-437. doi: 10.3324/haematol.2017.180778. Epub 2017 Dec 7. Haematologica. 2018. PMID: 29217778 Free PMC article. Clinical Trial.
RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia.
Lipka DB, Witte T, Toth R, Yang J, Wiesenfarth M, Nöllke P, Fischer A, Brocks D, Gu Z, Park J, Strahm B, Wlodarski M, Yoshimi A, Claus R, Lübbert M, Busch H, Boerries M, Hartmann M, Schönung M, Kilik U, Langstein J, Wierzbinska JA, Pabst C, Garg S, Catalá A, De Moerloose B, Dworzak M, Hasle H, Locatelli F, Masetti R, Schmugge M, Smith O, Stary J, Ussowicz M, van den Heuvel-Eibrink MM, Assenov Y, Schlesner M, Niemeyer C, Flotho C, Plass C. Lipka DB, et al. Among authors: boerries m. Nat Commun. 2017 Dec 19;8(1):2126. doi: 10.1038/s41467-017-02177-w. Nat Commun. 2017. PMID: 29259247 Free PMC article. Clinical Trial.
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