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Page 1
Targeting IGF Perturbs Global Replication through Ribonucleotide Reductase Dysfunction.
Rieunier G, Wu X, Harris LE, Mills JV, Nandakumar A, Colling L, Seraia E, Hatch SB, Ebner DV, Folkes LK, Weyer-Czernilofsky U, Bogenrieder T, Ryan AJ, Macaulay VM. Rieunier G, et al. Among authors: bogenrieder t. Cancer Res. 2021 Apr 15;81(8):2128-2141. doi: 10.1158/0008-5472.CAN-20-2860. Epub 2021 Jan 28. Cancer Res. 2021. PMID: 33509941
Nuclear IGF1R Interacts with Regulatory Regions of Chromatin to Promote RNA Polymerase II Recruitment and Gene Expression Associated with Advanced Tumor Stage.
Aleksic T, Gray N, Wu X, Rieunier G, Osher E, Mills J, Verrill C, Bryant RJ, Han C, Hutchinson K, Lambert AG, Kumar R, Hamdy FC, Weyer-Czernilofsky U, Sanderson MP, Bogenrieder T, Taylor S, Macaulay VM. Aleksic T, et al. Among authors: bogenrieder t. Cancer Res. 2018 Jul 1;78(13):3497-3509. doi: 10.1158/0008-5472.CAN-17-3498. Epub 2018 May 7. Cancer Res. 2018. PMID: 29735545 Free PMC article.
CHK1 inhibition exacerbates replication stress induced by IGF blockade.
Wu X, Seraia E, Hatch SB, Wan X, Ebner DV, Aroldi F, Jiang Y, Ryan AJ, Bogenrieder T, Weyer-Czernilofsky U, Rieunier G, Macaulay VM. Wu X, et al. Among authors: bogenrieder t. Oncogene. 2022 Jan;41(4):476-488. doi: 10.1038/s41388-021-02080-1. Epub 2021 Nov 12. Oncogene. 2022. PMID: 34773074 Free PMC article.
Chemoresistance in Pancreatic Cancer Is Driven by Stroma-Derived Insulin-Like Growth Factors.
Ireland L, Santos A, Ahmed MS, Rainer C, Nielsen SR, Quaranta V, Weyer-Czernilofsky U, Engle DD, Perez-Mancera PA, Coupland SE, Taktak A, Bogenrieder T, Tuveson DA, Campbell F, Schmid MC, Mielgo A. Ireland L, et al. Among authors: bogenrieder t. Cancer Res. 2016 Dec 1;76(23):6851-6863. doi: 10.1158/0008-5472.CAN-16-1201. Epub 2016 Oct 14. Cancer Res. 2016. PMID: 27742686 Free PMC article.
Antitumor Activity of the IGF-1/IGF-2-Neutralizing Antibody Xentuzumab (BI 836845) in Combination with Enzalutamide in Prostate Cancer Models.
Weyer-Czernilofsky U, Hofmann MH, Friedbichler K, Baumgartinger R, Adam PJ, Solca F, Kraut N, Nguyen HM, Corey E, Liu G, Sprenger CC, Plymate SR, Bogenrieder T. Weyer-Czernilofsky U, et al. Among authors: bogenrieder t. Mol Cancer Ther. 2020 Apr;19(4):1059-1069. doi: 10.1158/1535-7163.MCT-19-0378. Epub 2020 Feb 13. Mol Cancer Ther. 2020. PMID: 32054790 Free PMC article.
Two first-in-human studies of xentuzumab, a humanised insulin-like growth factor (IGF)-neutralising antibody, in patients with advanced solid tumours.
de Bono J, Lin CC, Chen LT, Corral J, Michalarea V, Rihawi K, Ong M, Lee JH, Hsu CH, Yang JC, Shiah HS, Yen CJ, Anthoney A, Jove M, Buschke S, Fuertig R, Schmid U, Goeldner RG, Strelkowa N, Huang DC, Bogenrieder T, Twelves C, Cheng AL. de Bono J, et al. Among authors: bogenrieder t. Br J Cancer. 2020 Apr;122(9):1324-1332. doi: 10.1038/s41416-020-0774-1. Epub 2020 Mar 12. Br J Cancer. 2020. PMID: 32161368 Free PMC article. Clinical Trial.
The molecular pathology of cutaneous melanoma.
Bogenrieder T, Herlyn M. Bogenrieder T, et al. Cancer Biomark. 2010;9(1-6):267-86. doi: 10.3233/CBM-2011-0164. Cancer Biomark. 2010. PMID: 22112480 Review.
56 results