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E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration.
Sladky VC, Knapp K, Soratroi C, Heppke J, Eichin F, Rocamora-Reverte L, Szabo TG, Bongiovanni L, Westendorp B, Moreno E, van Liere EA, Bakker B, Spierings DCJ, Wardenaar R, Pereyra D, Starlinger P, Schultze S, Trauner M, Stojakovic T, Scharnagl H, Fava LL, Foijer F, de Bruin A, Villunger A. Sladky VC, et al. Among authors: bongiovanni l. Dev Cell. 2020 Feb 10;52(3):335-349.e7. doi: 10.1016/j.devcel.2019.12.016. Epub 2020 Jan 23. Dev Cell. 2020. PMID: 31983631 Free article.
Atypical E2f functions are critical for pancreas polyploidization.
Matondo RB, Moreno E, Toussaint MJM, Tooten PCJ, van Essen SC, van Liere EA, Youssef SA, Bongiovanni L, de Bruin A. Matondo RB, et al. Among authors: bongiovanni l. PLoS One. 2018 Jan 12;13(1):e0190899. doi: 10.1371/journal.pone.0190899. eCollection 2018. PLoS One. 2018. PMID: 29329320 Free PMC article.
OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis.
Verboom L, Martens A, Priem D, Hoste E, Sze M, Vikkula H, Van Hove L, Voet S, Roels J, Maelfait J, Bongiovanni L, de Bruin A, Scott CL, Saeys Y, Pasparakis M, Bertrand MJM, van Loo G. Verboom L, et al. Among authors: bongiovanni l. Cell Rep. 2020 Feb 18;30(7):2237-2247.e6. doi: 10.1016/j.celrep.2020.01.028. Cell Rep. 2020. PMID: 32075762 Free article.
E2F7 Is a Potent Inhibitor of Liver Tumor Growth in Adult Mice.
Moreno E, Toussaint MJM, van Essen SC, Bongiovanni L, van Liere EA, Koster MH, Yuan R, van Deursen JM, Westendorp B, de Bruin A. Moreno E, et al. Among authors: bongiovanni l. Hepatology. 2021 Jan;73(1):303-317. doi: 10.1002/hep.31259. Hepatology. 2021. PMID: 32259305 Free PMC article.
PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis.
Sladky VC, Knapp K, Szabo TG, Braun VZ, Bongiovanni L, van den Bos H, Spierings DC, Westendorp B, Curinha A, Stojakovic T, Scharnagl H, Timelthaler G, Tsuchia K, Pinter M, Semmler G, Foijer F, de Bruin A, Reiberger T, Rohr-Udilova N, Villunger A. Sladky VC, et al. Among authors: bongiovanni l. EMBO Rep. 2020 Dec 3;21(12):e50893. doi: 10.15252/embr.202050893. Epub 2020 Nov 23. EMBO Rep. 2020. PMID: 33225610 Free PMC article.
Modeling Phenotypic Heterogeneity of Glycogen Storage Disease Type 1a Liver Disease in Mice by Somatic CRISPR/CRISPR-associated protein 9-Mediated Gene Editing.
Rutten MGS, Derks TGJ, Huijkman NCA, Bos T, Kloosterhuis NJ, van de Kolk KCWA, Wolters JC, Koster MH, Bongiovanni L, Thomas RE, de Bruin A, van de Sluis B, Oosterveer MH. Rutten MGS, et al. Among authors: bongiovanni l. Hepatology. 2021 Nov;74(5):2491-2507. doi: 10.1002/hep.32022. Epub 2021 Aug 15. Hepatology. 2021. PMID: 34157136 Free PMC article.
180 results