Bonn T - Search Results

1

Molecular basis of agonism and antagonism in the oestrogen receptor.

Brzozowski AM, Pike AC, Dauter Z, Hubbard RE, Bonn T, Engström O, Ohman L, Greene GL, Gustafsson JA, Carlquist M. Brzozowski AM, et al. Among authors: bonn t. Nature. 1997 Oct 16;389(6652):753-8. doi: 10.1038/39645. Nature. 1997. PMID: 9338790

2

Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist.

Pike AC, Brzozowski AM, Hubbard RE, Bonn T, Thorsell AG, Engström O, Ljunggren J, Gustafsson JA, Carlquist M. Pike AC, et al. Among authors: bonn t. EMBO J. 1999 Sep 1;18(17):4608-18. doi: 10.1093/emboj/18.17.4608. EMBO J. 1999. PMID: 10469641 Free PMC article.

3

Structural aspects of agonism and antagonism in the oestrogen receptor.

Pike AC, Brzozowski AM, Walton J, Hubbard RE, Bonn T, Gustafsson JA, Carlquist M. Pike AC, et al. Among authors: bonn t. Biochem Soc Trans. 2000;28(4):396-400. Biochem Soc Trans. 2000. PMID: 10961927 Review.

4

Structural insights into the mechanisms of agonism and antagonism in oestrogen receptor isoforms.

Hubbard RE, Pike AC, Brzozowski AM, Walton J, Bonn T, Gustafsson JA, Carlquist M. Hubbard RE, et al. Among authors: bonn t. Eur J Cancer. 2000 Sep;36 Suppl 4:S17-8. doi: 10.1016/s0959-8049(00)00207-0. Eur J Cancer. 2000. PMID: 11056300

5

Characterization of bacterially expressed rat estrogen receptor beta ligand binding domain by mass spectrometry: structural comparison with estrogen receptor alpha.

Witkowska HE, Carlquist M, Engström O, Carlsson B, Bonn T, Gustafsson JA, Shackleton CH. Witkowska HE, et al. Among authors: bonn t. Steroids. 1997 Aug-Sep;62(8-9):621-31. doi: 10.1016/s0039-128x(97)00047-0. Steroids. 1997. PMID: 9292936

6

Carboxymethylation of the human estrogen receptor ligand-binding domain-estradiol complex: HPLC/ESMS peptide mapping shows that cysteine 447 does not react with iodoacetic acid.

Hegy GB, Shackleton CH, Carlquist M, Bonn T, Engström O, Sjöholm P, Witkowska HE. Hegy GB, et al. Among authors: bonn t. Steroids. 1996 Jun;61(6):367-73. doi: 10.1016/0039-128x(96)00042-6. Steroids. 1996. PMID: 8776799

7

The three-dimensional structure of the liver X receptor beta reveals a flexible ligand-binding pocket that can accommodate fundamentally different ligands.

Färnegårdh M, Bonn T, Sun S, Ljunggren J, Ahola H, Wilhelmsson A, Gustafsson JA, Carlquist M. Färnegårdh M, et al. Among authors: bonn t. J Biol Chem. 2003 Oct 3;278(40):38821-8. doi: 10.1074/jbc.M304842200. Epub 2003 Jun 20. J Biol Chem. 2003. PMID: 12819202 Free article.

8

A novel analytical tool for quantification of estrogenicity in river water based on fluorescence labelled estrogen receptor alpha.

Le Blanc AF, Albrecht C, Bonn T, Fechner P, Proll G, Pröll F, Carlquist M, Gauglitz G. Le Blanc AF, et al. Among authors: bonn t. Anal Bioanal Chem. 2009 Nov;395(6):1769-76. doi: 10.1007/s00216-009-3038-8. Epub 2009 Aug 26. Anal Bioanal Chem. 2009. PMID: 19707746

9

Discovery of phenyl acetic acid substituted quinolines as novel liver X receptor agonists for the treatment of atherosclerosis.

Hu B, Collini M, Unwalla R, Miller C, Singhaus R, Quinet E, Savio D, Halpern A, Basso M, Keith J, Clerin V, Chen L, Resmini C, Liu QY, Feingold I, Huselton C, Azam F, Farnegardh M, Enroth C, Bonn T, Goos-Nilsson A, Wilhelmsson A, Nambi P, Wrobel J. Hu B, et al. Among authors: bonn t. J Med Chem. 2006 Oct 19;49(21):6151-4. doi: 10.1021/jm0609566. J Med Chem. 2006. PMID: 17034119

10

Indazole-based liver X receptor (LXR) modulators with maintained atherosclerotic lesion reduction activity but diminished stimulation of hepatic triglyceride synthesis.

Wrobel J, Steffan R, Bowen SM, Magolda R, Matelan E, Unwalla R, Basso M, Clerin V, Gardell SJ, Nambi P, Quinet E, Reminick JI, Vlasuk GP, Wang S, Feingold I, Huselton C, Bonn T, Farnegardh M, Hansson T, Nilsson AG, Wilhelmsson A, Zamaratski E, Evans MJ. Wrobel J, et al. Among authors: bonn t. J Med Chem. 2008 Nov 27;51(22):7161-8. doi: 10.1021/jm800799q. J Med Chem. 2008. PMID: 18973288

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