Borgnia MJ - Search Results

1

Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP₂.

Yin Y, Zhang F, Feng S, Butay KJ, Borgnia MJ, Im W, Lee SY. Yin Y, et al. Among authors: borgnia mj. Science. 2022 Oct 14;378(6616):eadd1268. doi: 10.1126/science.add1268. Epub 2022 Oct 14. Science. 2022. PMID: 36227998 Free PMC article.

2

Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel.

Yin Y, Le SC, Hsu AL, Borgnia MJ, Yang H, Lee SY. Yin Y, et al. Among authors: borgnia mj. Science. 2019 Mar 1;363(6430):eaav9334. doi: 10.1126/science.aav9334. Epub 2019 Feb 7. Science. 2019. PMID: 30733385 Free PMC article.

3

Regulatory switch at the cytoplasmic interface controls TRPV channel gating.

Zubcevic L, Borschel WF, Hsu AL, Borgnia MJ, Lee SY. Zubcevic L, et al. Among authors: borgnia mj. Elife. 2019 May 9;8:e47746. doi: 10.7554/eLife.47746. Elife. 2019. PMID: 31070581 Free PMC article.

4

Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.

Zubcevic L, Hsu AL, Borgnia MJ, Lee SY. Zubcevic L, et al. Among authors: borgnia mj. Elife. 2019 May 15;8:e45779. doi: 10.7554/eLife.45779. Elife. 2019. PMID: 31090543 Free PMC article.

5

Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.

Yin Y, Wu M, Hsu AL, Borschel WF, Borgnia MJ, Lander GC, Lee SY. Yin Y, et al. Among authors: borgnia mj. Nat Commun. 2019 Aug 20;10(1):3740. doi: 10.1038/s41467-019-11733-5. Nat Commun. 2019. PMID: 31431622 Free PMC article.

6

Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.

Suo Y, Wang Z, Zubcevic L, Hsu AL, He Q, Borgnia MJ, Ji RR, Lee SY. Suo Y, et al. Among authors: borgnia mj. Neuron. 2020 Mar 4;105(5):882-894.e5. doi: 10.1016/j.neuron.2019.11.023. Epub 2019 Dec 19. Neuron. 2020. PMID: 31866091 Free PMC article.

7

Heat-dependent opening of TRPV1 in the presence of capsaicin.

Kwon DH, Zhang F, Suo Y, Bouvette J, Borgnia MJ, Lee SY. Kwon DH, et al. Among authors: borgnia mj. Nat Struct Mol Biol. 2021 Jul;28(7):554-563. doi: 10.1038/s41594-021-00616-3. Epub 2021 Jul 8. Nat Struct Mol Biol. 2021. PMID: 34239123 Free PMC article.

8

Dromedary camel nanobodies broadly neutralize SARS-CoV-2 variants.

Hong J, Kwon HJ, Cachau R, Chen CZ, Butay KJ, Duan Z, Li D, Ren H, Liang T, Zhu J, Dandey VP, Martin NP, Esposito D, Ortega-Rodriguez U, Xu M, Borgnia MJ, Xie H, Ho M. Hong J, et al. Among authors: borgnia mj. Proc Natl Acad Sci U S A. 2022 May 3;119(18):e2201433119. doi: 10.1073/pnas.2201433119. Epub 2022 Apr 27. Proc Natl Acad Sci U S A. 2022. PMID: 35476528 Free PMC article.

9

Flipped over U: structural basis for dsRNA cleavage by the SARS-CoV-2 endoribonuclease.

Frazier MN, Wilson IM, Krahn JM, Butay KJ, Dillard LB, Borgnia MJ, Stanley RE. Frazier MN, et al. Among authors: borgnia mj. Nucleic Acids Res. 2022 Aug 12;50(14):8290-8301. doi: 10.1093/nar/gkac589. Nucleic Acids Res. 2022. PMID: 35801916 Free PMC article.

10

Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2.

Suo Y, Wright NJ, Guterres H, Fedor JG, Butay KJ, Borgnia MJ, Im W, Lee SY. Suo Y, et al. Among authors: borgnia mj. Nat Struct Mol Biol. 2023 Jul;30(7):1001-1011. doi: 10.1038/s41594-023-01017-4. Epub 2023 Jun 8. Nat Struct Mol Biol. 2023. PMID: 37291422 Free PMC article.

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