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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1977 1
1978 2
1979 3
1980 2
1981 2
1982 1
1983 5
1984 2
1985 1
1986 6
1987 7
1988 12
1989 12
1990 5
1991 5
1992 10
1993 11
1994 7
1995 10
1996 5
1997 9
1998 14
1999 13
2000 11
2001 5
2002 5
2003 12
2004 11
2005 7
2006 4
2007 7
2008 9
2009 6
2010 3
2011 8
2012 4
2013 5
2014 4
2015 3
2016 2
2017 1
2018 4
2019 2
2020 1
2021 1
2023 1
2024 0

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254 results

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Page 1
Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer.
Mertens S, Huismans MA, Verissimo CS, Ponsioen B, Overmeer R, Proost N, van Tellingen O, van de Ven M, Begthel H, Boj SF, Clevers H, Roodhart JML, Bos JL, Snippert HJG. Mertens S, et al. Among authors: bos jl. Cell Rep. 2023 Apr 25;42(4):112324. doi: 10.1016/j.celrep.2023.112324. Epub 2023 Mar 30. Cell Rep. 2023. PMID: 37000626 Free article.
An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity.
Kopper O, de Witte CJ, Lõhmussaar K, Valle-Inclan JE, Hami N, Kester L, Balgobind AV, Korving J, Proost N, Begthel H, van Wijk LM, Revilla SA, Theeuwsen R, van de Ven M, van Roosmalen MJ, Ponsioen B, Ho VWH, Neel BG, Bosse T, Gaarenstroom KN, Vrieling H, Vreeswijk MPG, van Diest PJ, Witteveen PO, Jonges T, Bos JL, van Oudenaarden A, Zweemer RP, Snippert HJG, Kloosterman WP, Clevers H. Kopper O, et al. Among authors: bos jl. Nat Med. 2019 May;25(5):838-849. doi: 10.1038/s41591-019-0422-6. Epub 2019 Apr 22. Nat Med. 2019. PMID: 31011202
Genetic alterations during colorectal-tumor development.
Vogelstein B, Fearon ER, Hamilton SR, Kern SE, Preisinger AC, Leppert M, Nakamura Y, White R, Smits AM, Bos JL. Vogelstein B, et al. Among authors: bos jl. N Engl J Med. 1988 Sep 1;319(9):525-32. doi: 10.1056/NEJM198809013190901. N Engl J Med. 1988. PMID: 2841597
Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling.
Ponsioen B, Post JB, Buissant des Amorie JR, Laskaris D, van Ineveld RL, Kersten S, Bertotti A, Sassi F, Sipieter F, Cappe B, Mertens S, Verlaan-Klink I, Boj SF, Vries RGJ, Rehmann H, Vandenabeele P, Riquet FB, Trusolino L, Bos JL, Snippert HJG. Ponsioen B, et al. Among authors: bos jl. Nat Cell Biol. 2021 Apr;23(4):377-390. doi: 10.1038/s41556-021-00654-5. Epub 2021 Apr 1. Nat Cell Biol. 2021. PMID: 33795873 Free PMC article.
Ras-like GTPases.
Bos JL. Bos JL. Biochim Biophys Acta. 1997 Oct 24;1333(2):M19-31. doi: 10.1016/s0304-419x(97)00015-2. Biochim Biophys Acta. 1997. PMID: 9395281 Review. No abstract available.
From Ras to Rap and Back, a Journey of 35 Years.
Bos JL. Bos JL. Cold Spring Harb Perspect Med. 2018 Feb 1;8(2):a031468. doi: 10.1101/cshperspect.a031468. Cold Spring Harb Perspect Med. 2018. PMID: 28778969 Free PMC article. Review.
DEP domains: structurally similar but functionally different.
Consonni SV, Maurice MM, Bos JL. Consonni SV, et al. Among authors: bos jl. Nat Rev Mol Cell Biol. 2014 May;15(5):357-62. doi: 10.1038/nrm3791. Epub 2014 Apr 16. Nat Rev Mol Cell Biol. 2014. PMID: 24739740 Review.
Specificity in Ras and Rap signaling.
Raaijmakers JH, Bos JL. Raaijmakers JH, et al. Among authors: bos jl. J Biol Chem. 2009 Apr 24;284(17):10995-9. doi: 10.1074/jbc.R800061200. Epub 2008 Dec 17. J Biol Chem. 2009. PMID: 19091745 Free PMC article. Review.
Epac proteins: multi-purpose cAMP targets.
Bos JL. Bos JL. Trends Biochem Sci. 2006 Dec;31(12):680-6. doi: 10.1016/j.tibs.2006.10.002. Epub 2006 Nov 2. Trends Biochem Sci. 2006. PMID: 17084085 Review.
254 results